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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 12 of 12. This is the beginning of the thread.
Posted by becksA on September 9, 2004, at 8:09:46
Having never tried MAOI's before, I don't really know what to expect. After doing abit of research I am thinking I want to try Parnate, for it's "stimulating" characteristics, and less side effects. ALthough I don't know much about Marplan. Insight much appreciated. Thanks
Posted by SLS on September 9, 2004, at 8:21:43
In reply to Nardil, Parnate or Marplan?? Confused!, posted by becksA on September 9, 2004, at 8:09:46
> Having never tried MAOI's before, I don't really know what to expect. After doing abit of research I am thinking I want to try Parnate, for it's "stimulating" characteristics, and less side effects. ALthough I don't know much about Marplan. Insight much appreciated. Thanks
Marplan has always been thought of by most psychiatrists as being a "weak" Nardil. That being said, there are some people who respond to Marplan who don't respond to Nardil, but this seems to be infrequent. Marplan definitely has milder side effects than Nardil, but probably is less effective in that it doesn't work for as many people. When it does work, it can work well.I tried Marplan once. I was silly enough to discontinue it after only two weeks because I wasn't feeling anything positive. I wasn't feeling anything negative either. It was much cleaner than either Parnate or Nardil with respect to startup side effects. I should have stayed on it for at least 4 weeks at a therapeutic dosage. I don't remember the dosage I worked up to.
Your reasons for going with Parnate make sense, especially if social phobia is not an issue.
Good luck with it.
- Scott
Posted by becksA on September 9, 2004, at 9:29:46
In reply to Re: Nardil, Parnate or Marplan?? Confused!, posted by SLS on September 9, 2004, at 8:21:43
Social Phobia/anxiety is actually my main reason for going on it....why do you bring that up? Should I avoid Parnate for social phobia?
Posted by iris2 on September 9, 2004, at 10:53:55
In reply to Re: Nardil, Parnate or Marplan?? Confused!, posted by SLS on September 9, 2004, at 8:21:43
I responded well to both Marplan and Parnate and some by the way to Moclobimide. (What about the reversible MAIO's?) I did not have any response to Nardil. My friend had a great response to Nardil and none at all to Parnate. Not sure if this is so infrequent.
irene
Posted by becksA on September 9, 2004, at 11:11:18
In reply to Re: Nardil, Parnate or Marplan?? Confused! » SLS, posted by iris2 on September 9, 2004, at 10:53:55
From what I gather, it's gonna be very hit or miss. Somewhat of a trial and error thing. Not sure what I'll even start with, might as well just go with Nardil as it seems the most effective if I had to pick one. Correct on this?
Posted by King Vultan on September 9, 2004, at 12:08:51
In reply to Re: Nardil, Parnate or Marplan?? Confused!, posted by becksA on September 9, 2004, at 11:11:18
> From what I gather, it's gonna be very hit or miss. Somewhat of a trial and error thing. Not sure what I'll even start with, might as well just go with Nardil as it seems the most effective if I had to pick one. Correct on this?
Probably, but it does have more side effects.
http://www.driesen.com/imoas.htm
Todd
Posted by iris2 on September 9, 2004, at 14:04:40
In reply to Re: Nardil, Parnate or Marplan?? Confused!, posted by becksA on September 9, 2004, at 11:11:18
Cannot seem to get to the site King Voltan posted. My personal experience was that Parnate had the most side effects of all three. It is waht my pdoc said too. That is all I know.
irene
Posted by becksA on September 9, 2004, at 14:13:07
In reply to Re: Nardil, Parnate or Marplan?? Confused! » becksA, posted by iris2 on September 9, 2004, at 14:04:40
Alright, well it seems to be that there are VERY mixed results on these drugs, although I havent heard much about Marplan, except that it is a "watered down version" of Parnate I believe it was. So i'll probably start on either Nardil or Parnate, whichever my pdoc recommends. If there's only 3 anyway, might as well just jump right on it, whichever one it is.
One last question, is if it's so great because it affects the 3 different parts of the brain, what is the difference betwen taking an MAOI and taking 3 individual meds that each target their respective part of the 3?
Thanks
Posted by Cruz on September 9, 2004, at 18:52:23
In reply to Re: Nardil, Parnate or Marplan?? Confused!, posted by becksA on September 9, 2004, at 14:13:07
> Alright, well it seems to be that there are VERY mixed results on these drugs, although I havent heard much about Marplan, except that it is a "watered down version" of Parnate I believe it was. So i'll probably start on either Nardil or Parnate, whichever my pdoc recommends. If there's only 3 anyway, might as well just jump right on it, whichever one it is.
>
> One last question, is if it's so great because it affects the 3 different parts of the brain, what is the difference betwen taking an MAOI and taking 3 individual meds that each target their respective part of the 3?
>
> ThanksThe mode of action of any psychoactive medication is not known. I have suffered with my disorder all my life I am 45 now. Parnate has been helpfull to me, unfortunatly that help only lasts for 3 months. After April,May and June I discontinue it and try other treatments. This has been my program for 20 years. Probably 30 years ago I suspected my disorder was an endocrine imbalance. They are slowly getting closer to understanding endocrine based mood disorders. Time will tell but most mood disorders could be endocrine based and not monominergic.
Posted by Sad Panda on September 9, 2004, at 23:31:26
In reply to Re: Nardil, Parnate or Marplan?? Confused! » SLS, posted by iris2 on September 9, 2004, at 10:53:55
Parnate is usually the first one to try because the other two are hepatotoxic.
Cheers,
Paul.
Posted by Ilene on September 10, 2004, at 0:00:42
In reply to Nardil, Parnate or Marplan?? Confused!, posted by becksA on September 9, 2004, at 8:09:46
> Having never tried MAOI's before, I don't really know what to expect. After doing abit of research I am thinking I want to try Parnate, for it's "stimulating" characteristics, and less side effects. ALthough I don't know much about Marplan. Insight much appreciated. Thanks
I'm taking Marplan with good results at 50 mg. and minimal side effects. I don't think it's "watered down" anything.
Posted by SLS on September 10, 2004, at 13:01:44
In reply to Re: Nardil, Parnate or Marplan?? Confused!, posted by Ilene on September 10, 2004, at 0:00:42
> I'm taking Marplan with good results at 50 mg. and minimal side effects. I don't think it's "watered down" anything.I agree. I don't think it is a valid characterization of Marplan to say that it is a "watered down" or "weaker" version of Nardil. It probably doesn't work for as many people statistically, but when it does work, it works just as well.
- Scott
This is the end of the thread.
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