Psycho-Babble Medication Thread 387930

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Amphetamines update/L-Glutamine

Posted by MindReseacher on September 8, 2004, at 3:08:51

Hi, about 10 days ago, i posted a bunch of info and questions on adderall, and amphetamines. I basically was getting ready to take an amphetamine holiday.
Well, let me tell you. I needed it. BUT, for 7 days, i was like a zombie, i could not function right, semi dysphoric, no motivation, sleeping all day, lack of interest in most everything. I wouldnt even answer my phone!.
To be brief, i was taking 60-90 mg of adderall, which is a high dose. I had a few days worth of Ritalin which did help, but i still noticed a difference. Then, i went to just plain ol caffiene, which did absolutely nothing, and I even took a few Ephedrine tablets , which did nothing but make my heart pound, gave me a little energy, but not mental, thats for sure.
So today, I got my refill, took my dose, and within 2 hrs, i felt 80 percent better, ( I could say 100 percent, but then i may be borderline saying just im high, but im not)
But im doing so much more work, im more social, calm, yet energetic, organized. My cravings for opiates are alot less, im very intersted in getting back to my research and daily activities.
Now, this time, i want to do things right. Taking Supplements such as L-Tyrosine, L-Theanine, Mucana Prurriens, all produce natural dopamine, which will help the adderall not "burn out" or loose its effect.
Also, taking an NMDA antagonist, to help lower amphetamine tolerance, which a recent study i read, possibly L-Theanine my do this.

A quick question: Taking L-Glutamine supplement, I use it for muscle recovery, Is a precursor to Glutamic acid. Now with this Effect Amphetamines? From what it looks like, due to the precursor to Glutamic acid, which actually effects opiate tolerance, may interact with amphetamines in a negative way.
I know all about the acidity of the stomach and Urine, which will decrease the amphetamine tolerance, but is tough to do, because i dont feel like drinking Baking soda, and Tums dont help. Possibly natural methods of reducing stomach acid, yet moresoe Urine alkaline will increase the effects of Amphetamine, or eliminate amphetamine "burnout" as i call it.

There are so many different ways to do this or that. Take this or that, it gets very confusing. But i know in about 1 week, my tolerance to 30mg of adderall will drastically increase. And amphetamines do release dopamine stored, i can possibly say that taking a Dopaminergic precusor, L-Tyrosine, or a Herbal like substance called Mucuna Prurriens,(15%l-dopa), studie show increases dopamine like the drug L-dopa, possibly better.(via supersmart.com)

Other alternatives, like nootropics may be an option, a few NDMA antagonists such as Memantine. Dopamine Agonists, a slew of them iv found on the psychobabble drug listing, But Mao's seem to be dangerous , and would not risk taking them with any stimulants.

One thing for sure is, after 2 months of daily use of amphetamines, a few days to a week is needed for amphetamine tolerance. The downside is that you dont feel like doing anything, to sum it up, your a zombie, dysphoric, sleeping, hermit!.lol. I guess a different mechanism type med like Desipramine, or even Ritalin, which even though is used for ADHD, and is similar to adderall, it does block the reuptake of Da/NA instead of release. But im not sure if this would help while taking off amphetamines.

Well any imput id appritiate, thank you for reading this.
MindResearch

 

Re: Quetion for MindResearcher Re Adderall » MindReseacher

Posted by Charm on September 8, 2004, at 11:54:37

In reply to Amphetamines update/L-Glutamine, posted by MindReseacher on September 8, 2004, at 3:08:51

Hi MR -

A few questions, please!

I am presently taking 30mg of Adderall XL. I've been taking this for close to two months now. Also, my pdoc has added 300 mg of Wellbutrin XL -- I took 150 for a month and am now in my second week of the 300mg. I believe she plans to stop here at 300mg. (Please note that in addition to these I take 150mg of Effexor, 45mg per day of Buspar, and 400mg a day of Ultram.)

My question really relates to the Adderall. It sounds like you've put in your research time on this med and I was hoping you wouldn't mind helping with a few questions.

Are you using the long acting formula or the immediate release formula? I wanted to know if you found one more effective than the other. Can someone take more than the 30mg of the Adderall XL or is this the max dose? For me, I find the roughly 9 hours that it is effective is not really long enough for me. However, my pdoc is stuck on the thought that I only really need it for work, while I personally know my high level of disorganization, lateness, and lack of focus affect me all day long...not just while I'm at the office.

I do use the baking soda/Alka Seltzer thing prior to taking the medicine hoping to increase its effectiveness. (I really have a taste for salt so I don't mind at all mixing it with a bottle of water.) How long before taking the Adderall should I use the baking soda so that it has time to work? Do you know if the second release is literally in four hours and if so, should I use the baking soda again at this time.

Finally, do you find 1 or 2 days off every couple of months sufficient for reducing tolerance?

Thanks a million for your help!

Charm

 

Re: Quetion for MindResearcher Re Adderall

Posted by CareBear04 on September 10, 2004, at 1:21:14

In reply to Re: Quetion for MindResearcher Re Adderall » MindReseacher, posted by Charm on September 8, 2004, at 11:54:37

hi,
like charm, i have a question about the 30mg max for adderall xr. why is it that the PDR says that 60mg is the max for immediate release adderall while 30mg is the limit for xr? i had an appt today with my pdoc, and i was taking 25mg twice a day-- i needed that much to offset lithium, which seems to cancel out the effects of adderall. b/c of this listed max dose, and because i wanted to try the xr, i'm now llimited to 30mg/day. i'm starting the xr tomorrow, and i hope that it's more potent and effective that the generic tabs i've been taking. if anyone has any experience or advice, i'd appreciate it.
thanks! cb

 

Re: Quetion for MindResearcher Re Adderall

Posted by craig getty on September 10, 2004, at 19:27:57

In reply to Re: Quetion for MindResearcher Re Adderall » MindReseacher, posted by Charm on September 8, 2004, at 11:54:37

What's this about alka seltzer/baking soda increasing the effectiveness of adderrall? How does it work and how should they be taken?

I'd appreciate any info on this....


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