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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by denise1904 on August 16, 2004, at 23:52:18
Just wondering if anyone knows what the latest is as far as research on Depression and possible new treatments goes? Don't mention rTMS as have just completed 14 sessions of it and it hastn't done anything so far. But don't let that put other people off as I've heard it can work just not on me "yet again". Feeling very sorry for myself right now.
Over the last three years I've heard of various things being in development, CRF Antagonists, Peptide P drugs but they never seem to come to fruitition.
Also, still can't understand why SSRIs don't work for me like they used to anymore, people just keep saying to me "Well your brain changes as you get older' but they worked for me for almsot 10 years (I realise how lucky I was after reading some of the posts on here) how come my brain stayed pretty much the same for all those years in order for them to work and how come it suddenly "changed in my mid 30s"? And if that's the case, I wonder what's in store for me in another 10 years time, is my brain gonna change some more and I'll be even worse??
I just don't get it anymore, the more I read the more confused I get and nothing makes sense. Everybody on here seems to have their own theories but there doestn't seem to be anything substantial.
Also, another thing which doestn't make sense to me is why is it that these researchers and Doctors seem to go by the theory that these antidepressants take at least 4 weeks to work and this is because of Neurogenesis or something. When they worked for me they worked within days?? My Doctor says this istn't possible, like I was lying to him or something??
And what's happening with these MRI scans, are they showing anything? Does anyone know?
I'm so sick and tired of this being an issue. I'm in Vancouver, the weather's been beautiful and I'm sitting here miserable and fed up.
Denise.
Posted by jlbl2l on August 17, 2004, at 8:30:45
In reply to Anything new on the Horizon? Need some hope., posted by denise1904 on August 16, 2004, at 23:52:18
Lyrica (pregabalin)
Posted by jrbecker on August 17, 2004, at 11:17:14
In reply to Anything new on the Horizon? Need some hope., posted by denise1904 on August 16, 2004, at 23:52:18
> Just wondering if anyone knows what the latest is as far as research on Depression and possible new treatments goes? Don't mention rTMS as have just completed 14 sessions of it and it hastn't done anything so far. But don't let that put other people off as I've heard it can work just not on me "yet again". Feeling very sorry for myself right now.
>
> Over the last three years I've heard of various things being in development, CRF Antagonists, Peptide P drugs but they never seem to come to fruitition.
>
> Also, still can't understand why SSRIs don't work for me like they used to anymore, people just keep saying to me "Well your brain changes as you get older' but they worked for me for almsot 10 years (I realise how lucky I was after reading some of the posts on here) how come my brain stayed pretty much the same for all those years in order for them to work and how come it suddenly "changed in my mid 30s"? And if that's the case, I wonder what's in store for me in another 10 years time, is my brain gonna change some more and I'll be even worse??
>
> I just don't get it anymore, the more I read the more confused I get and nothing makes sense. Everybody on here seems to have their own theories but there doestn't seem to be anything substantial.
>
> Also, another thing which doestn't make sense to me is why is it that these researchers and Doctors seem to go by the theory that these antidepressants take at least 4 weeks to work and this is because of Neurogenesis or something. When they worked for me they worked within days?? My Doctor says this istn't possible, like I was lying to him or something??
>
> And what's happening with these MRI scans, are they showing anything? Does anyone know?
>
> I'm so sick and tired of this being an issue. I'm in Vancouver, the weather's been beautiful and I'm sitting here miserable and fed up.
>
>
> Denise.
>
>
>
>http://www.neurotransmitter.net/newdrugs.html
http://www.sciam.com/article.cfm?articleID=00083A00-318C-1F30-9AD380A84189F2D7&pageNumber=1&catID=2
Posted by jrbecker on August 17, 2004, at 15:11:06
In reply to Re: Anything new on the Horizon? Need some hope. » denise1904, posted by jrbecker on August 17, 2004, at 11:17:14
Posted by denise1904 on August 17, 2004, at 19:03:15
In reply to Anything new on the Horizon? Need some hope., posted by denise1904 on August 16, 2004, at 23:52:18
Thanks so much for your responses, I'll check out this information.
Just wanted to say also that I've recommended this site to another person who suffers from depression because I think this site is the best and the support and knowledge on here is better than any other.
I just wish the Psychiatrists and people treating people would make it their business to make "themselves" a bit more knowledgeable.
Denise
Posted by sjb on August 18, 2004, at 10:15:32
In reply to Re: Anything new on the Horizon? Need some hope., posted by denise1904 on August 17, 2004, at 19:03:15
Couldn't agree more with both of your posts. It's very frustrating.
PS - Vancouver a place I always wanted to visit. I love to hike (when I'm feeling semi-normal!!)
Posted by jtevers on August 18, 2004, at 18:45:22
In reply to Re: Anything new on the Horizon? Need some hope. » denise1904, posted by jrbecker on August 17, 2004, at 11:17:14
jrbecker and all,
i had been diagnosed bipolar with psychosis several years ago and have been on several medications since then.
while effective, none has been without harrowing side-effects especially insomnia and weight gain ... i have gained 60 lbs. since my 2000 diagnosis.
can you help? i was so impressed by the outpouring of support and information offered the original "poster", i thought i would inquire for myself...
does "neurotransmitter.net" also follow up on the antipsychotic "pipeline"? i would just like to know if there MAY be a light at the end of this tunnel. I have been dissatisfied with current treatment options offered people with schizophrenia and bipolar suffering with psychosis.
can anyone help me find information on the future of psychosis treatment?
thank you
john
Posted by jrbecker on August 19, 2004, at 11:07:16
In reply to Re: Anything new on Horizon? Need some hope...help, posted by jtevers on August 18, 2004, at 18:45:22
> jrbecker and all,
>
> i had been diagnosed bipolar with psychosis several years ago and have been on several medications since then.
>
> while effective, none has been without harrowing side-effects especially insomnia and weight gain ... i have gained 60 lbs. since my 2000 diagnosis.
>
> can you help? i was so impressed by the outpouring of support and information offered the original "poster", i thought i would inquire for myself...
>
> does "neurotransmitter.net" also follow up on the antipsychotic "pipeline"? i would just like to know if there MAY be a light at the end of this tunnel. I have been dissatisfied with current treatment options offered people with schizophrenia and bipolar suffering with psychosis.
>
> can anyone help me find information on the future of psychosis treatment?
>
> thank you
> johnJohn,
Unfortunately, I’m not well informed on psychosis and the research, but I was able to some digging…
Keep hope and stay strong...
Good information on the newest antipsychotics in clinical trials
http://psychmeds.healingwell.com/same…
http://www.schizophrenia.com/ami/meds/bipoltreat.htmla review of antipsychotic meds in detail…
http://www.inetce.org/articles/pdf/146-000-02-039-H01.pdfan article on the genetics and neurobiology in Bipolar Disorder
http://www.medscape.com/viewarticle/458704The Off-Label Treatments for Bipolar Disorder
http://www.medscape.com/viewarticle/458706Bipolar Disorder, Obesity, and Pharmacotherapy-Associated Weight Gain
http://www.medscape.com/viewarticle/469420?src=searchNeuroimaging in Bipolar Disorder
http://www.medscape.com/viewarticle/471566?src=searchPosters & Abstracts: New Research in Mood Disorders
http://www.medscape.com/viewarticle/470354Clinical Update in Bipolar Disorders: Second-Generation Antipsychotics in the Maintenance Therapy of Bipolar Disorder
http://www.medscape.com/viewprogram/2496?src=searchUseful sites:
Medscape resource center on Bipolar disorder:
http://www.medscape.com/pages/editorial/resourcecenters/public/bipolardisorder/rc-bipolardisorder.ov?src=hp12.rctopMcMan’s Depression and Bipolar website
www.mcmanweb.com this is a great resource for new research and current issues regarding mental health. Sign up for their free newsletterhttp://www.narsad.org this is a national foundation that supports the most-cutting edge research on affective disorders. Sign up for their free quarterly newsletter. They talk quite a bit about the latest research on bipolar/psychosis.
Everyone else, please feel free to chime in.
JB
Posted by jtevers on August 21, 2004, at 12:15:29
In reply to Re: Anything new on Horizon? Need some hope...help, posted by jrbecker on August 19, 2004, at 11:07:16
JB,
thanx for your help. i appreciate the research you have done.
john
This is the end of the thread.
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