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Posted by katia on April 4, 2004, at 0:06:29
In reply to Re: Do antidepressants really work? - francesco, posted by rainbowlight on April 1, 2004, at 13:41:32
Hey Rainbow Light,
I just restarted Lam. and I LOVE it too. It's so euphoric feeling even at low doses. It's gives me my mojo back baby!You mention OCD? What are your symptoms? I think I may have that as well. I'm super sensitive to sensory stimulation and become bizarrely outraged when it feels as tho' I"m being invaded by sensory overload, i.e. noises being the worst of all. I love sound, when in the right context, i.e. music, birds, etc. but DETEST that boom boom music (should be outlawed) and dogs barking and blah blah blah. It drives me INSANE!!!! Is this OCD? I also have real problems w/ snoring or w/ people shaking their legs. It drives me crazy and has done since I was 11 - I'm 33 now. I feel crazy like a complete maniac in class when someone is moving their legs, I am almost driven to kill them.
anyway. what are your symptoms? Are you BP? I am BPII
thanks!
Katia
Posted by snapper on April 4, 2004, at 1:11:10
In reply to Re: Do antidepressants really work? - francesco » rainbowlight, posted by katia on April 4, 2004, at 0:06:29
Hey Katia, are you kidding? The noise thing is not a figment of your immagination-- I have OCD. Too much noise drives me at times into super maniacal RAAAAAGE! It sucks- little things like a horn honking, a dog barking, -sadly even the sound of my dad chewing his food at the table, makes me want to jump out of my skin!! Sound sensitivity and hyperacusis is not limited to ocd it also exists in many forms of mental Illnesse's
The Good news is this- -at least for me-when my depression clears up- MY oversensitivity to noises
tends to diminish. All I know is that I HAVE TO HAVE my fan going and an air purifier going to drown out any extra noise when I try going to sleep!! The thing about loud booming stereos's is really funny cuz I used to have an incredible amount of wattage and volume in my car stereos's- in fact it was one of my major hobbies- But now when i am in the car I barely want to even have the radio on!!!
So, no you ain't the only one!! I like my sound when I like my sound!!!
snapper
Posted by katia on April 4, 2004, at 4:15:22
In reply to Re: Do antidepressants really work? - francesco, posted by snapper on April 4, 2004, at 1:11:10
really funny snapper...my air purifier is going as I read your post. I'm almost in bed....
LOL. And my poor poor daddy. I remember one morning yearssss ago - probably 14 years ago when I was 19/20, I woke up and shuffled to coffee and yelled at him "do you have to make soooo much noise eating your cereal????". He just turned and looked at me and said "god, katia, you are sooo hard to live with". That shut me up for good. I haven't forgotten it. I cringe when I think about what I said to my poor father.Is this OCD? I'm dxed as BP.
Katia
Posted by Althea8869 on April 4, 2004, at 10:39:34
In reply to Do antidepressants really work?, posted by lexman on March 29, 2004, at 20:23:39
Ive seen this question many times and I think most have answered it pretty accurately, but I thought, 'its sunday morning and i'll throw my two, maybe three cents in'.
Two things we know for sure, 1) Depression is an illness(disease) and is characterized by particular neurological and physical symptoms which can be measured using a number of different methods, one of the most scientific is Proton Emmission Tomography (PET). Brain scans of depressed people (both endogenous and exogenous) show a clear differentiation from those not suffering. 2) We also know that certain medications over a period of several weeks will have a marked affect on the results of those brain scans - returning them to a more 'normal' state, if you will.
While this is good news, it must be pointed out that 1) The placebo effect must not be underestimated - the very act of thinking that a medication is going to work for you can often cause improvement - and not just in the short term as others have suggested. I have told the story before of patients in a trial of a cancer drug losing all their hair, despite, as it turned out, being given the placebo. They truly believed they would lose their hair and so they did. It didnt matter that they were taking sugar pills. 2) There is now an abundance of clinical evidence to show that psychotherapy alone results in precisely the same changes to PET scans that medication shows. (Not all medications, but many) Moreover, psychotherapy alone has been linked to longer term remission rates - no 'poop out'. This is why we are always advised that the best solution is both medication and psychotherapy in combination. 3) Its important to remember that the people that are most often used in the clinical trials that determine efficacy have an exogenous form of depression, typically short term. In other words they select the people MOST likely to respond to the medication - which across most medications shows ~35-50% some improvement and 25-35% significant improvement - and these results are for their 'taylor made' group. Said differently, these are not real world results. Typically you should divide those numbers in half for 'real world' application - and those numbers divided in half, surprise, surprise, are roughly the equivalent of the 'placebo' response group in most trials.
While it may seem that the picture is fairly bleak for medications, in reality its not that bad, actually its pretty good. The reason being that 1) There are so many different meds out there now (all of which have different chemical structures and most of which work by different mechanisms), and so many different forms of depression, that the probability of an individual responding to one of them is actually quite high - on the order of about 70%+. Its just a question of finding the correct match. This is why we constantly tell each other to go back to the doc and ask for something different. In fact there is a great deal of work being done now to better understand who will respond to what. This should improve initial response rates in the very near future. 2) We also know that combinations of meds can be complementary - something unthinkable just ten years ago. 3) The US government is starting to take this disease far more seriously than it ever did in the past - that translates into research dollars 4) Most importantly, thanks to advances in medical technology, our understanding of the human brain and its many functions, neurochemicals, interactions etc, has increased a thousand fold in just the last few years. The NE/SE/DO model of depression is now just one of many. There are leading edge psychopharmacologists that believe the next wave of medications will use a completely different model and target a completely different set of neurotransmitters - most of these meds dont have names right now, but they are being developed as we speak. 5) Finally, and best of all, there are sites like this one that allow sufferers to learn more about medications and the particulars of their conditions, similarities etc, as well as to form friendships and inspire in each of us a sense of helping others - which always makes me feel a little better. One truth is that an educated patient has a far greater chance for success than an uneducated one. This is true regardless of the condition. Kudoz to Dr Bob - i think he underestimates the true potential of a board like this. Bob if you ever need any financial assistance to keep this going, dont ever hesitate to ask.
I guess what this all distills down to is that, 'yes' antidepressants do work, but until we know more about neurochemistry and can better diagnose different kinds of depressive states, it will continue to be a trial and error process. For some a positive response may come quickly, for others, like me, it may take many years to find the right med or combination that works. Just dont give up, and always convey your experiences to others in formats like this. And dont ever forget about excersize/nutrition. In concert with the right meds, it can increase the level of improvement dramatically.
Anyway, take care and enjoy your sunday. I know that writing this has already put me in a good mood.
Posted by snapper on April 4, 2004, at 13:18:10
In reply to Re: Do antidepressants really work?, posted by Althea8869 on April 4, 2004, at 10:39:34
Althea, very well said!
Posted by snapper on April 4, 2004, at 13:29:52
In reply to Re: Do antidepressants really work? - francesco » snapper, posted by katia on April 4, 2004, at 4:15:22
Hi Katia, if you are diagnosed as BP then there is a very good chance that you may have a 'co-morbid' disorder along with the primary disorder as well. For example- Many people who have BP II , like my self- tend to have a cluster of BP II -Social Anxiety and many times OCD as well - what a nasty trio of things going on in our heads... You may or may not have OCD- and if you want to know for sure then just do a search on the net for OCD and look past the normal symptoms of repeatingly wanting to wash your hands or checking the door a thousand times or making sure the stove is off a bunch of times etc. OCD in my experience, manifests itself in MANY different ways in different people- also the mere diagnosis of BP disorder can mimic the symptoms of OCD. Hope that helps clarify things. All I know is that OCD sufferers do tend to be overwhelmed with intense overload of sensory stimuli, etc. But so do ADD and ADHD people, it is hard to figure out. But to me there is just so much overlap in all these disorders!!
Snapper
Posted by SLS on April 4, 2004, at 13:33:38
In reply to Re: Do antidepressants really work?, posted by Althea8869 on April 4, 2004, at 10:39:34
> .. it must be pointed out that 1) The placebo effect must not be underestimated - the very act of thinking that a medication is going to work for you can often cause improvement
Whenever I hear this, I wonder how precisely the participants in the study are screened for an unequivocal biological depression. For instance, would the rate of placebo response be the same between DST suppressors and non-suppressors? What about the more severe cases that display psychomotor retardation? I would love to see a study testing for the placebo effect among exclusively DST non-suppressors.
BTW, you did a marvelous job with your post.
- Scott
Posted by katia on April 4, 2004, at 16:09:43
In reply to Re: Do antidepressants really work? - francesco, posted by snapper on April 4, 2004, at 13:29:52
> Hi Katia, if you are diagnosed as BP then there is a very good chance that you may have a 'co-morbid' disorder along with the primary disorder as well. For example- Many people who have BP II , like my self- tend to have a cluster of BP II -Social Anxiety and many times OCD as well - what a nasty trio of things going on in our heads... You may or may not have OCD- and if you want to know for sure then just do a search on the net for OCD and look past the normal symptoms of repeatingly wanting to wash your hands or checking the door a thousand times or making sure the stove is off a bunch of times etc. OCD in my experience, manifests itself in MANY different ways in different people- also the mere diagnosis of BP disorder can mimic the symptoms of OCD. Hope that helps clarify things. All I know is that OCD sufferers do tend to be overwhelmed with intense overload of sensory stimuli, etc. But so do ADD and ADHD people, it is hard to figure out. But to me there is just so much overlap in all these disorders!!
> SnapperHi Snapper,
Does OCD ever go away on it's own or change faces?
When I was little, I HAD to have my room in tip top shape, even w/ my little purse hanging just right on the door handle before I went to sleep. My mother would have to shut the door just right or I'd go bazeerk if the purse moved off center. I don't have that anymore though. Wierd, back then, no one questioned that behavior (70's). At least not my parents. Something was making me out act like that, whether it had to do w/ my environment or in my head.I also had very intense phobias, like fear of losing a leg, losing my hair, getting cancer, spiders, etc. All about when I was 10/11. Then as a teenager, I went wild. My room was a disaster and I no longer needed order. In fact chaos ruled and then came panic attacks and depression. So who knows. You're right. They all look the same (these disorders) and it could very well be BP symptoms.
thanks for you input.
Katia
Posted by snapper on April 4, 2004, at 16:51:00
In reply to OCD or BP? » snapper, posted by katia on April 4, 2004, at 16:09:43
> > Hi Katia, if you are diagnosed as BP then there is a very good chance that you may have a 'co-morbid' disorder along with the primary disorder as well. For example- Many people who have BP II , like my self- tend to have a cluster of BP II -Social Anxiety and many times OCD as well - what a nasty trio of things going on in our heads... You may or may not have OCD- and if you want to know for sure then just do a search on the net for OCD and look past the normal symptoms of repeatingly wanting to wash your hands or checking the door a thousand times or making sure the stove is off a bunch of times etc. OCD in my experience, manifests itself in MANY different ways in different people- also the mere diagnosis of BP disorder can mimic the symptoms of OCD. Hope that helps clarify things. All I know is that OCD sufferers do tend to be overwhelmed with intense overload of sensory stimuli, etc. But so do ADD and ADHD people, it is hard to figure out. But to me there is just so much overlap in all these disorders!!
> > Snapper
>
> Hi Snapper,
> Does OCD ever go away on it's own or change faces?
> When I was little, I HAD to have my room in tip top shape, even w/ my little purse hanging just right on the door handle before I went to sleep. My mother would have to shut the door just right or I'd go bazeerk if the purse moved off center. I don't have that anymore though. Wierd, back then, no one questioned that behavior (70's). At least not my parents. Something was making me out act like that, whether it had to do w/ my environment or in my head.
>
> I also had very intense phobias, like fear of losing a leg, losing my hair, getting cancer, spiders, etc. All about when I was 10/11. Then as a teenager, I went wild. My room was a disaster and I no longer needed order. In fact chaos ruled and then came panic attacks and depression. So who knows. You're right. They all look the same (these disorders) and it could very well be BP symptoms.
> thanks for you input.
> Katia
>Hi Katia, yes OCD can change the way it presents it self over time-- It seems that when I was young, and OCD first presented itself I was also afraid of 'things'! Afraid of household cleaners (chemicals) potential poisons etc. As I grew older I new that their were some thing about me that were quirky- But the OCD just kinda laid in the background and then teen years and early adulthood I figured out that masking a lot of my phobias and fears etc-came in the form of alcohol!I exp my 1st major dep. episode when I was 23-and then my OCD flaied up and had some specific phobias etc. When I came out of that episode and I started my own Business and was blessed with extrordinary success-but I had to 'always be in control' perfectionism set in and I found it hard to deligate responsibility to others-who were ,most likely capable of taking care of the day to day biz affairs-when I would go on vacations to get away from my "self emposed" standards of orderliness and perfectionism-- I would find it was very hard to relax and found Myself calling back to my office to see if everything was going ok or just right!!! Not to bore you but the mere fact that I felt I had to be in control of things to be done in precise order, was part of my eventual demise and downfall
ongoing tension, stress, anxiety and of course depression. I also helped myself self- destruct - by continuing to medicate-with alcohol and then of course another OCD spectrum disorder> Pathological gambling!! When I was semi-manic or feeling just right!! I felt invincible at blackjack and found my self to be hyper-perceptive in playing the game-I could most always
"Win and make huge gains! However , cuz of the repetetiveness of the OCD I never felt that 'It' was enough- so even if I could turn $50 into $500 or a few hundred into several thousand, IT WAS NEVER ENOUGH !! IT was not just greed it was the fact that I just wanted to play "ONE MORE HAND" and ultimately in the end the 'tables turned ' and the house won . Then instead of me playing with the Casinos' money and being satisfied with my winnings, I would end up losing tens and hundreds of thousands of dollars over a 5-6 year period!! The river boat casinos' here in my town -were ultimately ONE of the very biggest facors in my emotional collapse. Between the addiction of alcohol and the destuctive behaviour of needing to go back to the Casinos'- tore me down-I lost everything- banned my self from the casinos' (a state law that allows permanent banning from all the casinos's in Missouri- if I walk on to one and they ask me for ID- the system is immediately flagged that I am on the Black List and security will immediately come and arrest me for "Tresspassing" - I HAD to do this becasue I was either going to kill myself through the addictive behaviour or by the rediculous and sometimes fraudulent ways of obtaining more $$$$ to continue to Gamble- I AM DAMN LUCKY I AM NOT IN JAIL AND I HAVE VERY LOVING AND UNDERSTANDING PARENTS/FAMILY!So in regards to OCD manifesting itself in many different ways; yes It certainly does!!! Not everyone w/OCD has these probems-obviously but I am sure that there are literally millions of people out there who are having extreme and painful problems in life with respect to the self defating and VERY destrucive behaviours. I'm sorry If I've gotten off track here- I tend to do that- that in itself -at least in myself is a clear indication of OCD--- The need to feel that all details are NOT left out and the story needs to be explaind just right! It is very hard but am trying to re-build my life one step at a time !! Hope you don't suffer to the extent that I have described but hopefully may give you some insight into things that might be able to help yourself or potentially others out there - I firmly believe that If you "know whats wrong" you can work more effectively at correcting and fixing the things that are wrong!!! Your original ?, yes sometimes OCD and its ugly symptoms do lessen to a great degree or go away altogether for some!!
snapper
Posted by Althea8869 on April 4, 2004, at 22:34:08
In reply to Re: Do antidepressants really work? » Althea8869, posted by SLS on April 4, 2004, at 13:33:38
Scott - please excuse my acronym ignorance, but what is DST?
Never the less, your point is well taken. I also wonder about the inclusion/exclusion criteria. I see two significant problems. First, it doesnt appear that the trials process is representative of our current body of knowledge on neurological disorders. We are way past the 'one size fits all' mentality which I suspect governed much of the process as recently as five years ago. Clinical testing must become far more targeted and precise - we have enough knowledge now to be well along this path and yet we are not. Second, the pharmaceuticals are still far too involved in the process. After submission for clinical testing, they should be completely divorced from the process, having no input or control over any part of either the trials or the corresponding reports of results.
Solve these problems and two things will happen: we will have far more accurate data about efficacy and response rates across the whole spectrum of neurological disorders, and, we will introduce a measure of integrity into a system which few patients currently trust.
Just my thoughts.
Hope you had a nice Sunday.
Take it easy.
Posted by SLS on April 5, 2004, at 8:11:17
In reply to Re: Do antidepressants really work?, posted by Althea8869 on April 4, 2004, at 22:34:08
> Scott - please excuse my acronym ignorance, but what is DST?
DST = dexamethasone suppression test
Dexamethasone is a synthetic cortisol. In a negative feedback loop arrangement, ACTH secreted by the pituatary gland stimulates the adrenal glands to secrete cortisol. In healthy people, an increase in the blood level of cortisol signals the pituitary gland to reduce its output of ACTH. So too does the introduction of dexamethasone. However, in a sizable percentage of people diagnosed with major depression, dexamethasone fails to suppress the secretion of ACTH. The negative feedback loop fails to limit cortisol production. The DST was investigated intensively during the 1980s, and was used to aid in the diagnosis of endogenous depression.
Some studies suggest that people who are non-suppressors (abnormal) are statistically more severely depressed and, perhaps more importantly, more likely to respond to ECT or medication than suppressors.
- Scott
Posted by Althea8869 on April 5, 2004, at 9:28:11
In reply to Re: Do antidepressants really work? » Althea8869, posted by SLS on April 5, 2004, at 8:11:17
Fascinating! Apparently I have not been keeping up with my homework here. Why is this test not more widely utilized as a marker? Is it a cost issue(no insurance coverage) or is it a safety issue for the patient or possibly a question of validity of findings and causal relationships.
Need to do some research. I'll check back later.
Thanks Scott.
Take care.
Posted by simus on April 5, 2004, at 11:16:38
In reply to Re: Do antidepressants really work? » Althea8869, posted by SLS on April 5, 2004, at 8:11:17
Scott,
I am trying to digest this info. The reason being, I have always wondered if what I really needed to go to was an endricrinologist years ago instead of a psychiatrist for the sudden onset of anxiety/panic attacks. It just felt more like an adrenaline flood than a "mental" illness, which made me wonder about the proper function of the adrenal glands. I have also wondered if my hypothalamus was working properly (strong intolerance to heat).
I don't know how familiar you are on the topic, but I will run this past you. I have never had total success on a SSRI. The best success I have up to 3 months ago had was on a SNRI. Now on Wellbutrin alone, I feel great emotionally. But I have some symptoms that I think appear to be adrenal related. For instance, extreme edema, and a sudden onset of pain/achyness/stiffness. I am grasping at straws here, but I thought I would throw this all at you to see what you knew.
Thanks in advance. God bless.
Posted by jdgjdg on April 5, 2004, at 21:56:44
In reply to OCD or BP? » snapper, posted by katia on April 4, 2004, at 16:09:43
I have both OCD and BP I. It took a long time for my pdoc to diagnose the bp because I withheld a lot of information from her because I was afraid. OCD can and often does come and go. It seems to have triggers(and often doesn't have any triggers) just as any other disorder. OCD is primarily characterized by disruptive thoughts that cause you to repeat rituals such as hand washing, checking the door, locks, oven,etc. There are also many other compulsions that someone can have. Someone with OCD can also have what they call avoidance compulsions. That is simply avoiding a situation that causes the thoughs to race out of control. I can describe it best like this: When I am obsessing, it's like having a song stuck in my head. It just won't go away. The more I try to get the scary thought out of my head, the more I keep thinking of it. To make the thought go away, I will check and re check the windows, doors, and locks to insure my safety. My obsessions are usually about my safety. The more I check, the worse the obsessive thoughts get. Does this make sense? There is a website you can visit. www.ocfoundation.org I think you will find it useful. Jenn
Posted by snapper on April 5, 2004, at 23:04:08
In reply to Re: Do antidepressants really work? » Althea8869, posted by SLS on April 5, 2004, at 8:11:17
> > Scott - please excuse my acronym ignorance, but what is DST?
>
> DST = dexamethasone suppression test
>
> Dexamethasone is a synthetic cortisol. In a negative feedback loop arrangement, ACTH secreted by the pituatary gland stimulates the adrenal glands to secrete cortisol. In healthy people, an increase in the blood level of cortisol signals the pituitary gland to reduce its output of ACTH. So too does the introduction of dexamethasone. However, in a sizable percentage of people diagnosed with major depression, dexamethasone fails to suppress the secretion of ACTH. The negative feedback loop fails to limit cortisol production. The DST was investigated intensively during the 1980s, and was used to aid in the diagnosis of endogenous depression.
>
> Some studies suggest that people who are non-suppressors (abnormal) are statistically more severely depressed and, perhaps more importantly, more likely to respond to ECT or medication than suppressors.
>
>
> - Scott> Hi Scott, you are correct on the DST thing. At least in my experience. When I had the DST done in 1992' and was almost disappointed that it came back as normal, so to speak. I thought, how come that test came back neg. for me. I wanted a real reason for why I felt so awful. I thought it was a definitive type thing but we obviously know it is not!! Would'nt it be nice if it were that simple?
snapper
Posted by katia on April 5, 2004, at 23:38:37
In reply to Re: OCD or BP?, posted by jdgjdg on April 5, 2004, at 21:56:44
Yes, you make perfect sense. I don't really experience that though. I can see how one could get stuck in that spiral tho'. To me, it's the anxiety that would make the thoughts go round and round, feeling like I was not in control, but being controlled and caged by this tormenting thought/song...The more I could let go and not let it torment me, the less it would become. We're prisoners to the fear of something controlling/caging us. I think that's a big part of it. And so then you do something to alleviate it - enter in the compulsion side.
For me it's more about noise. I feel caged and induces anxiety when I'm stuck listening to unpleasant sounds. or a wierd one is when people jitter or shake their legs. it's been murder being a student. I'm surrounded by people shaking their legs during class. I can't explain it, but it drives me insane. I remember the first time it bothered me when I was 11 in a classroom and a big boy next to me shook his leg sooo fast all the time it drove me mad. And since then I can't take it (I'm 33!). It induces anger, intolerance, a feeling of being caged and subjected to torture. perhaps it's too stimulating for me? I dunno. it's very odd indeed. Who knows. it could be some unconscious association w/ a trauma that happened for me at that time - although I don't remember what the trauma is?!
I just figured I had a touch of OCD to have such a wierd making crazy thing like shaking legs!
Katia
Posted by simus on April 6, 2004, at 0:25:06
In reply to Re: OCD or BP? » jdgjdg, posted by katia on April 5, 2004, at 23:38:37
> For me it's more about noise. I feel caged and induces anxiety when I'm stuck listening to unpleasant sounds. or a wierd one is when people jitter or shake their legs. it's been murder being a student. I'm surrounded by people shaking their legs during class. I can't explain it, but it drives me insane. I remember the first time it bothered me when I was 11 in a classroom and a big boy next to me shook his leg sooo fast all the time it drove me mad. And since then I can't take it (I'm 33!). It induces anger, intolerance, a feeling of being caged and subjected to torture.
I understand exactly. There are things that trigger me too, like soup slurping. I literally have to leave the room if someone is slurping their soup. Or there are those who can't seem to take a drink of something without following it EVERY TIME with an "Ahhhh". Or the people who can't sneeze without some sort of a shreiking noise - that they insist they can't control it. Even the "kissing noises" on TV during a romantic scene ruin the show for me. And then there are the "gum snappers" in church, of all places. Sometimes it irritates me to the point of being afraid that I won't be able to contain myself. I know it is really MY problem, but just telling yourself to ignore it DOES NOT WORK!!!
Posted by simus on April 6, 2004, at 0:35:48
In reply to Re: Do antidepressants really work? » Althea8869, posted by SLS on April 5, 2004, at 8:11:17
Scott,
You have some very intriguing information. What is your source?
Posted by katia on April 6, 2004, at 2:59:55
In reply to Re: OCD or BP? » katia, posted by simus on April 6, 2004, at 0:25:06
Have you been dxed w/ OCD? B/c what you described sounds like me. What is it about this intolerance of people's annoying habits that drive us around the bend? I don't get it. But it is a form of torture.
Katia
Posted by SLS on April 6, 2004, at 8:02:10
In reply to Re: Do antidepressants really work?, posted by snapper on April 5, 2004, at 23:04:08
> > Hi Scott, you are correct on the DST thing. At least in my experience. When I had the DST done in 1992' and was almost disappointed that it came back as normal, so to speak. I thought, how come that test came back neg. for me. I wanted a real reason for why I felt so awful. I thought it was a definitive type thing but we obviously know it is not!! Would'nt it be nice if it were that simple?
> snapper
I know.The DST is by no means specific and sensitive enough to be a global test for biological depression. Many people with biological depression do show normal suppression. I guess this is yet another indication that "depression" is a multifactorial presentation, the exact etiology of which is complex and varies from individual to individual.
I can only guess how you must have felt when your DST came back normal. The results did not "vindicate" you of having any control or responsibility for your mood states, which you in fact have very little. It must have been confusing and unsettling.
- Scott
Posted by SLS on April 6, 2004, at 8:11:07
In reply to Re: Do antidepressants really work? » SLS, posted by simus on April 6, 2004, at 0:35:48
> Scott,
>
> You have some very intriguing information. What is your source?Hi Simus.
DST has been around for a long time. It is used not only for depression, but for other cortisol abnormalities as well. Your best bet is to do a search on google:
http://www.google.com/search?hl=en&ie=UTF-8&oe=UTF-8&q=dst+depression
Here is a review that helps verify the validity of the DST for identifying endogenous depressions, both unipolar and bipolar:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8909334
Have fun.
- Scott
Posted by simus on April 6, 2004, at 12:16:58
In reply to Re: OCD or BP? » simus, posted by katia on April 6, 2004, at 2:59:55
> Have you been dxed w/ OCD? B/c what you described sounds like me. What is it about this intolerance of people's annoying habits that drive us around the bend? I don't get it. But it is a form of torture.
> KatiaYes, and I have been like this as far back as I can remember. I wish I wasn't this way. I am not judgemental and these are really nice people. I just can't stand their "noises". Maybe instead of drugs, the doc should give me earplugs. lol Actually, it does work. =) When my first daughter was born, she had colic and a very, very high pitched scream. I thought I was going to lose my mind for about a month, until I bought some earplugs.
Posted by simus on April 6, 2004, at 12:22:10
In reply to Re: Do antidepressants really work? » simus, posted by SLS on April 6, 2004, at 8:11:07
Posted by katia on April 6, 2004, at 14:54:31
In reply to Re: OCD or BP? » katia, posted by simus on April 6, 2004, at 12:16:58
>>
> Yes, and I have been like this as far back as I can remember. I wish I wasn't this way. I am not judgemental and these are really nice people. I just can't stand their "noises". Maybe instead of drugs, the doc should give me earplugs. lol Actually, it does work. =) When my first daughter was born, she had colic and a very, very high pitched scream. I thought I was going to lose my mind for about a month, until I bought some earplugs.
>So, having these things that drive us crazy means OCD? I don't really have the compulsion side though. Do you? I own mannnny ear plugs! I can't even imagine having to endure a baby screaming and HAVING to be there and play mother and be patient w/o losing my mind and killing us both!
Good job in maintaining!
Katia
Posted by snapper on April 6, 2004, at 17:54:56
In reply to Re: OCD or BP? » simus, posted by katia on April 6, 2004, at 14:54:31
> >>
> > Yes, and I have been like this as far back as I can remember. I wish I wasn't this way. I am not judgemental and these are really nice people. I just can't stand their "noises". Maybe instead of drugs, the doc should give me earplugs. lol Actually, it does work. =) When my first daughter was born, she had colic and a very, very high pitched scream. I thought I was going to lose my mind for about a month, until I bought some earplugs.
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> So, having these things that drive us crazy means OCD? I don't really have the compulsion side though. Do you? I own mannnny ear plugs! I can't even imagine having to endure a baby screaming and HAVING to be there and play mother and be patient w/o losing my mind and killing us both!
> Good job in maintaining!
> KatiaHey Katia, the mere fact that things get on our nerves more so than others might be too simplistic I do know for sure that it is possible for ocd to potentially evolve into "primarally obsessional ocd" ie: obsessions but no apparent compulsions-however if you look deeper into the actual symptoms many times you will find that the obsessions are not the only thing present-but compulsions as well!! If you want, post me back and I'll try to explain what I mean.All I know is this:Since being off of FXR since last May or June 2003 I have been painfully aware of my obsessions and minor compulsions-its' Helllllll- I hate the idea that I might have to go back on effexor to control these problems, but it might be a neccessity
snapper
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