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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 12 of 12. This is the beginning of the thread.
Posted by roof8 on January 1, 2000, at 10:47:59
2 or 3 days ago, I posted the following message:
"I have to take Desyrel for the sleep in add"ition to an other SSRI AD.
But before taking it, I would like to know if anyone who take Desyrel is putting on weight with it, and how much ? "and no one answered. Is my question stupid, incomprehensible, or simply no one has experience with Desyrel in the US ?
Tanks for answer and happy new year.
Posted by S. Suggs on January 1, 2000, at 12:03:50
In reply to Is my english too bad?, posted by roof8 on January 1, 2000, at 10:47:59
What ssri are you taking? Trazadone may cause weight gain (not sure), probably due to the ssri.
Blessings,
S. Suggs
Posted by jamie on January 1, 2000, at 13:26:07
In reply to Is my english too bad?, posted by roof8 on January 1, 2000, at 10:47:59
> 2 or 3 days ago, I posted the following message:
>
> "I have to take Desyrel for the sleep in add"ition to an other SSRI AD.
> But before taking it, I would like to know if anyone who take Desyrel is putting on weight with it, and how much ? "
>
> and no one answered. Is my question stupid, incomprehensible, or simply no one has experience with Desyrel in the US ?
> Tanks for answer and happy new year.This is a popular subject actually. Many people have weight gain with SSRIs and/or Desyrel. These drugs can make us feel hungry more often and eat more when we eat. They probably modify body metabolism too. So yes Desyrel can cause weight gain. But not with everyone. I think we need to change our diets and exercise if we gain weight. But that is much easier said than done, isn't it. I couldn't do it. It's all I can do to just get by.
jamie
Posted by Scott L. Schofield on January 1, 2000, at 13:39:27
In reply to Re: Is my english too bad?, posted by jamie on January 1, 2000, at 13:26:07
> > 2 or 3 days ago, I posted the following message:
> >
> > "I have to take Desyrel for the sleep in add"ition to an other SSRI AD.
> > But before taking it, I would like to know if anyone who take Desyrel is putting on weight with it, and how much ? "
> > and no one answered. Is my question stupid, incomprehensible, or simply no one has experience with Desyrel in the US ?
> > Tanks for answer and happy new year.> This is a popular subject actually. Many people have weight gain with SSRIs and/or Desyrel. These drugs can make us feel hungry more often and eat more when we eat. They probably modify body metabolism too. So yes Desyrel can cause weight gain. But not with everyone. I think we need to change our diets and exercise if we gain weight. But that is much easier said than done, isn't it. I couldn't do it. It's all I can do to just get by.
>
> jamieYou seem to be getting some good replies now. I think Jamie’s explanation is a real good one.
Please, please don’t take it personally that no one responded to your first post. Your English is PERFECT. I think there were just so many posts to read, that some people got left out.
Good Luck.
Oh, and Happy New Year to you!
- Scott
Posted by roof8 on January 1, 2000, at 13:43:03
In reply to Re: Is my english too bad?, posted by S. Suggs on January 1, 2000, at 12:03:50
Thanks for your message.
I tried many SSRI's (Celexa, Zoloft) and other's like Serzone and effexor.
I'm not gaining weight with these medications. The problem is I can't sleep. And in addition of that, my depression is worsening when I take them. That's why I change every 3 or 4 weeks to try something else.
I'm actually trying 5-HTP (not a real SSRI but 5 HT precursor), but same problems.
I think I 'll try to carry on with this medic. and add Desyrel for sleep, if I don't gain more weight because of Desyrel. I have no better idea for the moment and I spend really bad time, while trying to find a solution.
Posted by JohnL on January 1, 2000, at 15:21:42
In reply to Re: Is my english too bad?, posted by roof8 on January 1, 2000, at 13:43:03
> Thanks for your message.
> I tried many SSRI's (Celexa, Zoloft) and other's like Serzone and effexor.
> I'm not gaining weight with these medications. The problem is I can't sleep. And in addition of that, my depression is worsening when I take them. That's why I change every 3 or 4 weeks to try something else.
> I'm actually trying 5-HTP (not a real SSRI but 5 HT precursor), but same problems.
> I think I 'll try to carry on with this medic. and add Desyrel for sleep, if I don't gain more weight because of Desyrel. I have no better idea for the moment and I spend really bad time, while trying to find a solution.Everything you've tried so far works primarily on serotonin. But you've gotten worse, right? I think there are many different chemical imbalances that cause depression. Not just serotonin. It sounds like your serotonin might be OK. That's why serotonin drugs aren't working. The problem I might guess is something else. If I were you I would seriously consider trying a medicine in a completely different class. I don't know if you can get Wellbutrin (Bupropion). If not, ask about Nortriptyline or Desipramine. You would likely need the Desyrel to sleep with Wellbutrin, but maybe not with Desipramine or Nortriptyline. These are all drugs that work on different chemical imbalances than the ones you've tried so far.
Have you ever had anything other than just depression? For example, mania? Or hypomania? Or psychosis? Wide mood swings between feeling real good and then feeling real bad? If yes, then an antidepressant of any kind might just make things worse. A mood stabilizer or two would be an approach to consider. It just seems to me that everything you've tried so far is pretty much the same, and they haven't worked, so it makes sense I think to look elsewhere. Nortriptyline, Desipramine, Wellbutrin, mood stabilizers. Something like that. JohnL
Posted by roof8 on January 3, 2000, at 16:00:17
In reply to Re: Is my english too bad?, posted by JohnL on January 1, 2000, at 15:21:42
Well, your right. In fact, I already tried "Ludiomil" which primarily works on NE instead of 5-HT, the effect was better. But I took about 8 Kilos (I don't know in US pounds) and I had urinary infections because it's anticholinergic (= diminish the size of urinary tract as side effect). That's why I had to stop it.
It will be probably the same with desipramine and nortriptyline, it's anticholinergic.
In switzerland we don't have Burpropion (wellbutrin) because I think it hasn't been accepted by health adminstration.I don't know where I can find information about AD which work primarily on NE.
What about Remeron ? I know it's not anticholinergic, but where does it works primarily 5-HT or NE ? and Desyrel ?
(for what Jhon asked, I'm not bipolar, but rapid mood change between normal and depression)
Esquisse.
Posted by JohnL on January 3, 2000, at 17:52:46
In reply to Re: Is my english too bad?, posted by roof8 on January 3, 2000, at 16:00:17
Here are a couple ideas for you. I'm not sure of the spelling, but there is a drug called Bethanechol. It is a cholinergic drug. It is used to counteract the anticholinergic side effects of antidepressants. If you can get Bethanechol, then you will have many more NE antidepressant options available to you.
Remeron works on both 5HT and NE by stimulating their release. Its primary side effects are sedation and weight gain.
But since you are in Switzerland, you should be able to get Amisulpride(Solian). It is an antipsychotic/antidepressant. I believe it's from Germany. Maybe France. Not sure. It works on dopamine, not 5HT or NE, and has been proven successful in clinical trials for depression, dysthymia, and the similar negative symptoms of schizophrenia. And it apparently works faster than the SSRIs. I tried a sample of it from a friend for a couple days and I like it a lot. It had no side effects other than a slightly dry mouth. And it was a little be activating, giving me more energy. My friend got it from a pharmacy in Switzerland. If I were you, I would definitely look for Amisulpride. We in the USA are missing out on a real good drug in Amisulpride.
Wish you well. JohnL
p.s. (if you can send me some Amisulpride, I WANT SOME) :)
Posted by roof8 on January 4, 2000, at 4:52:43
In reply to Re: Is my english too bad?-roof8, posted by JohnL on January 3, 2000, at 17:52:46
Sorry first, I sent an empty message.
Jhon, I could maybe find Solian for you here in switzerland. But I need a doctor prescription first. And even in that case, I don't know if they will give the medication if I'm not the person whose name is written on the prescription. But I could ask. Second problem: the transfer of money (how?)and the costs of the package shipping to US. I think it's as expensive as the medication itself. But if you are still interested we can discuss.
Esquisse.
Posted by JohnL on January 4, 2000, at 13:27:13
In reply to Re: Is my english too bad?-roof8, posted by roof8 on January 4, 2000, at 4:52:43
> Sorry first, I sent an empty message.
>
> Jhon, I could maybe find Solian for you here in switzerland. But I need a doctor prescription first. And even in that case, I don't know if they will give the medication if I'm not the person whose name is written on the prescription. But I could ask. Second problem: the transfer of money (how?)and the costs of the package shipping to US. I think it's as expensive as the medication itself. But if you are still interested we can discuss.
> Esquisse.Thank you very much for the offer. If I want it bad enough I think it is available from an overseas pharmacy with a prescription. I wouldn't seriously ask you to go through so much trouble. But I was touched by your generosity.
What I was really trying to do was get you interested enough to consider Amisulpride for yourself. If you want an uplifting antidepressant with few side effects, 50mg or 100mg should do it.
Thanks again. :) JohnL
Posted by JohnL 2 on January 4, 2000, at 13:35:16
In reply to Re: Is my english too bad?-roof8, posted by roof8 on January 4, 2000, at 4:52:43
After reading your post further down the page about your worsened depression on 5HTP + St Johnswort, I am even more convinced now that you should avoid any drug that works at all on 5HT. And I feel stronger than ever you should try a dopamine drug like Amisulpride. It would be completely different than anything you've tried yet. And the side effects are almost nothing. JohnL
Posted by anna on January 5, 2000, at 9:52:47
In reply to Is my english too bad?, posted by roof8 on January 1, 2000, at 10:47:59
> 2 or 3 days ago, I posted the following message:
>
> "I have to take Desyrel for the sleep in add"ition to an other SSRI AD.
> But before taking it, I would like to know if anyone who take Desyrel is putting on weight with it, and how much ? "
>
> and no one answered. Is my question stupid, incomprehensible, or simply no one has experience with Desyrel in the US ?
> Tanks for answer and happy new year.I didn't read the rest of the posts, but I take Zoloft and a low dose of desryl at night to sleep and have for years-.-I did initially put on weight--just about 5 pounds, but I was very thin and the zoloft was taken to combat a thing with eating I had. I find the two work well together for my panic and anixiety . I did however, have to add wellbruitrin a while ago when depression popped up.
--anna
This is the end of the thread.
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