Psycho-Babble Medication Thread 3700

Shown: posts 1 to 25 of 27. This is the beginning of the thread.

 

Effexor Tolerance

Posted by Tillman on March 14, 1999, at 21:56:27

Hello all. I just discovered this site. I tried to write to Dr. Bob and he suggested I stop in.

I have been taking 75 mg. of effexor a day for 2 years. I believe it may have lost its effect. I have heard that Prozac 'poops out' after awhile and people have to increase their dosage. Has anyone had this experience with effexor?

Also recently seeing notes from people talking about the withdrawal proeblems coming off of effexor has me a littel concerned. Would people recommend getting off now ... or increasing now and withdrawing later. The drug has been a wonder drug for me. The only side effect that I have had that I'm not thrilled with is that it has effected my sensitivity. While being a people pleaser to some extent this has it's benefits, I feel bad that I am not as sensitive and compassionate as I used to be before the medication. However the way it has helped my depression has been nothing short of amazing up until recently.

Any thoughts, help would be appreciated. Thanks and good luck to us all.

Til.

 

Re: Effexor Tolerance

Posted by Nick on March 15, 1999, at 14:30:54

In reply to Effexor Tolerance, posted by Tillman on March 14, 1999, at 21:56:27


> I have been taking 75 mg. of effexor a day for 2 years. I believe it may have lost its effect. I have heard that Prozac 'poops out' after awhile and people have to increase their dosage. Has anyone had this experience with effexor?
>
At 75mg/day, some authorities feel that Effexor is primarily an SSRI. 'Poop out' has been described with SSRIs - especially prozac, although that may eflect how popular prozac is - but seems ( to my understanding at least) to be less common with the older antidepressants which usually had a mixed or noradrenergic mechanism. If you push the dose of effexor up, you may start to get the benefit of the noradrenergic reuptake inhibition. Chat to your doc. All the best, Nick

 

Re: Effexor Tolerance

Posted by Tillman on March 16, 1999, at 0:36:07

In reply to Re: Effexor Tolerance, posted by Nick on March 15, 1999, at 14:30:54

>
> > I have been taking 75 mg. of effexor a day for 2 years. I believe it may have lost its effect. I have heard that Prozac 'poops out' after awhile and people have to increase their dosage. Has anyone had this experience with effexor?
> >
> At 75mg/day, some authorities feel that Effexor is primarily an SSRI. 'Poop out' has been described with SSRIs - especially prozac, although that may eflect how popular prozac is - but seems ( to my understanding at least) to be less common with the older antidepressants which usually had a mixed or noradrenergic mechanism. If you push the dose of effexor up, you may start to get the benefit of the noradrenergic reuptake inhibition. Chat to your doc. All the best, Nick

Nick, thank you very much for the reply. I appreciate your input.

 

Re: Effexor Tolerance

Posted by Wayne R. on March 16, 1999, at 10:31:07

In reply to Effexor Tolerance, posted by Tillman on March 14, 1999, at 21:56:27

> I have been taking 75 mg. of effexor a day for 2 years. I believe it may have lost its effect. I have heard that Prozac 'poops out' after awhile and people have to increase their dosage. Has anyone had this experience with effexor?
>
I have had the same experience with most medications, especially the ones considered SSRIs. They would all work for some variable time and then "poop out" even with increased dosage. See my posting "Naltrexone for SSRI poop out" in February to see what finally worked for me. Wayne

 

Re: Effexor Tolerance

Posted by Mark on March 25, 1999, at 6:06:27

In reply to Re: Effexor Tolerance, posted by Wayne R. on March 16, 1999, at 10:31:07

75 mg of Effexor is a very low dose. It certainly
pooped out relative to it's normal effectiveness
for you, but the dose of immediate release Effexor
can go over 400 mg and the dose of extended
release Effexor over 200 (and probable over 400
like the immediate release form (it just wasn't
studied enough at that dose)). I certainly
wouldn't give up on a med that worked when you
are far from the maximum dose (note also, that
many psychiatrists prescribe it at even higher
doses than I listed above).

As far as "withdrawal." There is indeed a
phenomena known as SSRI discontinuation syndrome
(SSRI being serotonin-specific reuptake inhibiter).
SSRI's include Prozac, Paxil, Zoloft...(Effexor
is similar but slightly different).
Discontinuation symptoms are real and uncomfortable
and, with some of the antidepressants listed
above, they can be difficult to avoid.
This said, discontinuation symptoms are not the
same as withdrawal symptoms---antidepressants
are not addictive and do not cause withdrawal
symptoms like alcohol, caffeine, nicotine or
heroin...The discontinuation symptoms are thought
to be the result of changes in serotonin levels
that make people feel like they are going through
a bad flu. Discontinuation symptoms are not
dangerous in any way. Effexor can also have
discontinuation symptoms. The only way to avoid
them is to taper the medications slowly.
Still, I wouldn't worry about them, they are mostly
nuisance problems.

> > I have been taking 75 mg. of effexor a day for 2 years. I believe it may have lost its effect. I have heard that Prozac 'poops out' after awhile and people have to increase their dosage. Has anyone had this experience with effexor?
> >
> I have had the same experience with most medications, especially the ones considered SSRIs. They would all work for some variable time and then "poop out" even with increased dosage. See my posting "Naltrexone for SSRI poop out" in February to see what finally worked for me. Wayne

 

Re: Effexor Tolerance - Mark

Posted by Elizabeth on March 28, 1999, at 2:23:30

In reply to Re: Effexor Tolerance, posted by Mark on March 25, 1999, at 6:06:27

> As far as "withdrawal." There is indeed a
> phenomena known as SSRI discontinuation syndrome

Discontinuation syndrome? There's a piece of double-speak I hadn't heard before. :-) Seriously, I do understand the need to dispell any belief that SSRIs might somehow be "addictive" (which doesn't mean anything in particular anyway), but the resulting word-play can be unwieldy. I take it that you consider "withdrawal" to be something that includes "cravings" as well as the substance-specific d/c syndrome?

(Perhaps notably, perhaps not, DSM-IV just calls these substance-specific syndromes "withdrawal." :-)

I've heard of people using Benadryl for the Paxil/Effexor/Zoloft d/c syndrome (don't see it so much with Prozac). Not sure which symptoms Benadryl is supposed to help with.

>(Effexor is similar but slightly different).

Yeah, this pretty much sums up the relationship between Effexor and the SSRIs - similar, except different.

 

Crying all the time

Posted by Mary Beth on May 4, 1999, at 14:24:16

In reply to Re: Effexor Tolerance, posted by Mark on March 25, 1999, at 6:06:27

After about 5 years on Prozac (it stopped working) I was on 150 mg. of Effexor for about 2 years.

I stopped the Effexor upon agreement with my Dr. that things are going very well and I might as well try it on my own. I went to the 75 mg. dose for 1 week, now I've been off entirely for 4 days.

I am having physical symptoms...the shocks when I move my head (not painful but almost dizzying). Also feel exhausted and stupid. I'm willing to wait those out...

What has me worried is the crying, or being ready to cry at any time. When I read something sad in the paper. When I read something happy in the paper. When I see something poignant on TV. I'm not talking about Touched by an Angel here...but just everyday "feel good" stories about the guy who turned in a lost wallet that he found.

Has anyone else had this emotional wackiness, and does it last?

Thanks! Mary Beth

 

Re: Effexor Tolerance

Posted by stjames on May 4, 1999, at 19:43:05

In reply to Effexor Tolerance, posted by Tillman on March 14, 1999, at 21:56:27

Take a look at last months posts on this...

james

 

Re: Crying all the time

Posted by saintjames on May 4, 1999, at 23:20:26

In reply to Crying all the time, posted by Mary Beth on May 4, 1999, at 14:24:16

>
> What has me worried is the crying, or being ready to cry at any time. When I read something sad in the paper. When I read something happy in the paper. When I see something poignant on TV. I'm not talking about Touched by an Angel here...but just everyday "feel good" stories about the guy who turned in a lost wallet that he found.

James here...

Well you are not alone ! The same happens to me
when I come off effexor. I take 1 mg atavin like every other day for a week. Call your doc....you don't have to live thru this w/o help. One or 2 doses of Prozac or restarting effexor will work.
Prozac has far less or no side effects in most.
I've tried all of these and prefer the atavin as my nerves are a little frayed at this point.

james

> Has anyone else had this emotional wackiness, and does it last?
>
> Thanks! Mary Beth

 

Re: Crying all the time

Posted by JD on May 5, 1999, at 5:59:32

In reply to Crying all the time, posted by Mary Beth on May 4, 1999, at 14:24:16

Sounds like a pretty quick schedule for coming off a med reputed to have some difficult withdrawal effects... Have you considered going back on at say 50 or 25mg and tapering over a period of weeks? Might be a bit easier both physically and psychologically, and you'd still be off it for good within a month or so...
Good luck,
- JD


>
> I stopped the Effexor upon agreement with my Dr. that things are going very well and I might as well try it on my own. I went to the 75 mg. dose for 1 week, now I've been off entirely for 4 days.
>
> I am having physical symptoms...the shocks when I move my head (not painful but almost dizzying). Also feel exhausted and stupid. I'm willing to wait those out...
>
> What has me worried is the crying, or being ready to cry at any time. When I read something sad in the paper. When I read something happy in the paper. When I see something poignant on TV. I'm not talking about Touched by an Angel here...but just everyday "feel good" stories about the guy who turned in a lost wallet that he found.
>
> Has anyone else had this emotional wackiness, and does it last?
>
> Thanks! Mary Beth

 

Re: Crying all the time

Posted by pat on May 6, 1999, at 23:53:04

In reply to Re: Crying all the time, posted by JD on May 5, 1999, at 5:59:32

see my post under Effexor withdrawal.

Also - I have had to take 1/2 mg. ativan (lorazepam) 2X a day all along to balance effects of effexor. I can't sleep without the ativan at night, and become very agitated if I don't take the afternoon dose.

 

Re: Effexor Tolerance - Mark

Posted by Mark on May 10, 1999, at 2:09:47

In reply to Re: Effexor Tolerance - Mark, posted by Elizabeth on March 28, 1999, at 2:23:30

The difference between addiction/withdrawal and
discontinuation is important. Addictive
substances like Ativan and Dexedrine (very
often used in psychiatry) exhibit tolerance
(you need more drug for the same effect)
and nearly immediate withdrawal symptoms that
can be dangerous. SSRI's and Effexor
don't show clear tolerance, although they
may not work except at higher doses in some
cases or they may poop out at times. When you
stop them, they have some nuisance effects like
stomach upset, flu-like symptoms, and
insomnia as opposed to dangerous withdrawal
symptoms like can occur with Ativan---seizures,
for example. The other difference is that Ativan,
Dexedrine and other addictive medications/drugs
do not treat disorders--they only treat symptoms.
SSRI's and Effexor, when they work, seem to do a
good job treating depression and anxiety disorders.

> > As far as "withdrawal." There is indeed a
> > phenomena known as SSRI discontinuation syndrome
>
> Discontinuation syndrome? There's a piece of double-speak I hadn't heard before. :-) Seriously, I do understand the need to dispell any belief that SSRIs might somehow be "addictive" (which doesn't mean anything in particular anyway), but the resulting word-play can be unwieldy. I take it that you consider "withdrawal" to be something that includes "cravings" as well as the substance-specific d/c syndrome?
>
> (Perhaps notably, perhaps not, DSM-IV just calls these substance-specific syndromes "withdrawal." :-)
>
> I've heard of people using Benadryl for the Paxil/Effexor/Zoloft d/c syndrome (don't see it so much with Prozac). Not sure which symptoms Benadryl is supposed to help with.
>
> >(Effexor is similar but slightly different).
>
> Yeah, this pretty much sums up the relationship between Effexor and the SSRIs - similar, except different.

 

Re: Effexor Tolerance - Mark

Posted by Elizabeth on May 10, 1999, at 9:25:34

In reply to Re: Effexor Tolerance - Mark, posted by Mark on May 10, 1999, at 2:09:47

> The difference between addiction/withdrawal and
> discontinuation is important. Addictive
> substances like Ativan and Dexedrine (very
> often used in psychiatry) exhibit tolerance
> (you need more drug for the same effect)
> and nearly immediate withdrawal symptoms that
> can be dangerous.

Hmm. It depends which effect you're talking about when you say people develop "tolerance" to them. To the best of my knowledge, the anxiolytic and antipanic effects of Ativan and the anti-ADD effects of Dexedrine generally persist without dosage creep. People using these drugs to get high will probably develop tolerance to the euphoria, though. Tolerance also builds up to sedation from Ativan and to appetite suppression from Dexedrine (again, if I recall correctly). But then again, one also can develop tolerance to the side effects of antidepressants; for example, nausea from Luvox, or elevations in systolic BP from Parnate (personal experience).

In regard to withdrawal syndromes: I won't debate Ativan, as it's true that it can cause seizures if discontinued abruptly. But about Dexedrine -
you might be interested to hear a quote that is kind of funny in retrospect. I had stopped taking Parnate because of an apparent adverse reaction. About two days later I saw my psychiatrist. He said: "You look awful! You look like someone who's coming down from a cocaine binge!" I thought this was a wacky thing to say, and I did some reading about cocaine and amphetamine withdrawal syndromes. The descriptions I read sounded very familiar. Not only did they resemble my Parnate "discontinuation syndrome," they also resembled the severe and refractory depression I developed after Nardil pooped out (except that I didn't have REM rebound as long as I stayed on Nardil, obviously - though that would have been the least of my troubles).

There are a couple of reports in the literature of people abusing large doses of MAOIs with no apparent cardiovascular problems, BTW. One assumes they had even nastier withdrawal symptoms, comparable to - well, perhaps to the sort of thing one experiences when coming down from a cocaine binge. I also imagine that for people who take moderate doses of Dexedrine, missing a day might be similar to what happens when I skip a day of Parnate (not horrible, but not pleasant either).

And as for treating the "symptom" versus the "disorder:" I disagree. I don't believe you can make this generalization. I think Ativan or Xanax is a fine treatment for panic disorder since they treat both the core symptom of panic attacks and the peripheral symptoms of anticipatory anxiety, phobic avoidance, etc. Similarly, it seems to me that Dexedrine a reasonable treatment for attention deficit hyperactivity disorder, in that it helps people with attention problems, hyperactivity, and impulsivity. (It's also a good treatment for narcolepsy.) I also found buprenorphine (which I'm guessing you would probably class as an "addictive" drug even though it has only a mild and delayed withdrawal syndrome - and of course opiate withdrawal is a classic example of "unpleasant but not life threatening") to be a very good treatment for major depressive disorder (except for the side effects, which were nasty). Am I misunderstanding what you mean when you say that antidepressants treat "the disorder?"

Well anyway, I don't think the difference between "addictive" and "nonaddictive" substances is as clear-cut as one might like.

 

Re: Effexor Tolerance

Posted by Tillman on May 31, 1999, at 0:08:37

In reply to Re: Effexor Tolerance, posted by Wayne R. on March 16, 1999, at 10:31:07

> > I have been taking 75 mg. of effexor a day for 2 years. I believe it may have lost its effect. I have heard that Prozac 'poops out' after awhile and people have to increase their dosage. Has anyone had this experience with effexor?
> >
> I have had the same experience with most medications, especially the ones considered SSRIs. They would all work for some variable time and then "poop out" even with increased dosage. See my posting "Naltrexone for SSRI poop out" in February to see what finally worked for me. Wayne

Thanks Wayne. I'll check your February Posting. I was having computer problems and am now just getting your reply. I have upped 25 mg to 100 mgs daily and it has helped so far. Thanks again.

 

Re: Effexor Tolerance

Posted by tillman on May 31, 1999, at 0:13:06

In reply to Re: Effexor Tolerance, posted by Mark on March 25, 1999, at 6:06:27

> 75 mg of Effexor is a very low dose. It certainly
> pooped out relative to it's normal effectiveness
> for you, but the dose of immediate release Effexor
> can go over 400 mg and the dose of extended
> release Effexor over 200 (and probable over 400
> like the immediate release form (it just wasn't
> studied enough at that dose)). I certainly
> wouldn't give up on a med that worked when you
> are far from the maximum dose (note also, that
> many psychiatrists prescribe it at even higher
> doses than I listed above).
>
> As far as "withdrawal." There is indeed a
> phenomena known as SSRI discontinuation syndrome
> (SSRI being serotonin-specific reuptake inhibiter).
> SSRI's include Prozac, Paxil, Zoloft...(Effexor
> is similar but slightly different).
> Discontinuation symptoms are real and uncomfortable
> and, with some of the antidepressants listed
> above, they can be difficult to avoid.
> This said, discontinuation symptoms are not the
> same as withdrawal symptoms---antidepressants
> are not addictive and do not cause withdrawal
> symptoms like alcohol, caffeine, nicotine or
> heroin...The discontinuation symptoms are thought
> to be the result of changes in serotonin levels
> that make people feel like they are going through
> a bad flu. Discontinuation symptoms are not
> dangerous in any way. Effexor can also have
> discontinuation symptoms. The only way to avoid
> them is to taper the medications slowly.
> Still, I wouldn't worry about them, they are mostly
> nuisance problems.
>
>
>
> > > I have been taking 75 mg. of effexor a day for 2 years. I believe it may have lost its effect. I have heard that Prozac 'poops out' after awhile and people have to increase their dosage. Has anyone had this experience with effexor?
> > >
> > I have had the same experience with most medications, especially the ones considered SSRIs. They would all work for some variable time and then "poop out" even with increased dosage. See my posting "Naltrexone for SSRI poop out" in February to see what finally worked for me. Wayne

Thanks a lot Mark for your informative and encouraging reply. I was having computer problems and am now just getting your reply. I have upped 25 mg to 100 mgs daily and it has helped so far. Thanks again.

 

Re: Crying all the time

Posted by tillman on May 31, 1999, at 0:18:27

In reply to Crying all the time, posted by Mary Beth on May 4, 1999, at 14:24:16

> After about 5 years on Prozac (it stopped working) I was on 150 mg. of Effexor for about 2 years.
>
> I stopped the Effexor upon agreement with my Dr. that things are going very well and I might as well try it on my own. I went to the 75 mg. dose for 1 week, now I've been off entirely for 4 days.
>
> I am having physical symptoms...the shocks when I move my head (not painful but almost dizzying). Also feel exhausted and stupid. I'm willing to wait those out...
>
> What has me worried is the crying, or being ready to cry at any time. When I read something sad in the paper. When I read something happy in the paper. When I see something poignant on TV. I'm not talking about Touched by an Angel here...but just everyday "feel good" stories about the guy who turned in a lost wallet that he found.
>
> Has anyone else had this emotional wackiness, and does it last?
>
> Thanks! Mary Beth

Thanks for your reply Mary Beth. I was having computer problems and am now just getting your reply. I have upped 25 mg to 100 mgs daily and it has helped so far.

Stat in touch with your progress on getting off effexor. From other postings that I have seen the symptoms are temporary. I'm assuming thaty you may be done with them by now. I hope so. Let me know how you are doing. tgoettelmann@genam.com.


 

Re: Crying all the time

Posted by Mary Beth on June 2, 1999, at 10:49:54

In reply to Re: Crying all the time, posted by tillman on May 31, 1999, at 0:18:27

No, the symptoms were WAY TOO BAD and I couldn't cope....also couldn't get in with my psychiatrist. It came at a particularly bad time, work-wise...So I went back to my GP and he prescribed some more for me (one week at 37.5 mg; next week at 75 mg; finally back up to 150 mg). The relief was amazing, with that first dose.....within a few hours I felt much much better.

I am still trying to get with the psychiatrist to get an appointment about this! Thanks for your message.

 

Re: Crying all the time

Posted by Gracie on June 2, 1999, at 22:14:10

In reply to Re: Crying all the time, posted by tillman on May 31, 1999, at 0:18:27

I was on effexor for about two years (75 mg 2X day.) After about two years it seemed to stop working for me, so my doctor put me on wellbutrin.
After weaning me off the effexor over a three month period, while on the wellbutrin, I started "falling apart". I had a lot of mood swings, feelings of deep sadness and grief, and many crying spells. We decided to reintroduce the effexor. At 75 mg effexor and 400 mg wellbutrin I was doing pretty well. I really want to wean myself off the effexor because it seems to be causing a weight gain (I've been on effexor a total of about four plus years), but every time I try to cut back even if very slowly (e.g. 75 mg to 62.5 mg) I start feeling very sad and the tears
and sadness resume. I made an appt. to see my doctor to explore options. The weight gain has really made me feel terrible about myself, yet I'm really afraid to fall back into another depression. I'd appreciate any feedback/suggestions from others with similar experiences.
Thanks !

 

Re: Effexor Tolerance

Posted by PattyGates on June 6, 1999, at 19:44:52

In reply to Effexor Tolerance, posted by Tillman on March 14, 1999, at 21:56:27

My son started out taking Effexor 100 mg. twice daily. When that began to wane, they tried 300, but that was too much. He then tried 150 SR and added Wellbutrin. This combination has been rather successful.

 

Re: Effexor Tolerance

Posted by tillman on June 6, 1999, at 22:53:05

In reply to Re: Effexor Tolerance, posted by PattyGates on June 6, 1999, at 19:44:52

> My son started out taking Effexor 100 mg. twice daily. When that began to wane, they tried 300, but that was too much. He then tried 150 SR and added Wellbutrin. This combination has been rather successful.

Thanks for the information Patty.

 

Re: Effexor Tolerance - Mark

Posted by Mark on June 16, 1999, at 3:22:56

In reply to Re: Effexor Tolerance - Mark, posted by Elizabeth on May 10, 1999, at 9:25:34

Well said. And don't get me wrong, whether or not
one thinks
of these medications as addictive or not,
they are all very effective as you described.


> > The difference between addiction/withdrawal and
> > discontinuation is important. Addictive
> > substances like Ativan and Dexedrine (very
> > often used in psychiatry) exhibit tolerance
> > (you need more drug for the same effect)
> > and nearly immediate withdrawal symptoms that
> > can be dangerous.
>
> Hmm. It depends which effect you're talking about when you say people develop "tolerance" to them. To the best of my knowledge, the anxiolytic and antipanic effects of Ativan and the anti-ADD effects of Dexedrine generally persist without dosage creep. People using these drugs to get high will probably develop tolerance to the euphoria, though. Tolerance also builds up to sedation from Ativan and to appetite suppression from Dexedrine (again, if I recall correctly). But then again, one also can develop tolerance to the side effects of antidepressants; for example, nausea from Luvox, or elevations in systolic BP from Parnate (personal experience).
>
> In regard to withdrawal syndromes: I won't debate Ativan, as it's true that it can cause seizures if discontinued abruptly. But about Dexedrine -
> you might be interested to hear a quote that is kind of funny in retrospect. I had stopped taking Parnate because of an apparent adverse reaction. About two days later I saw my psychiatrist. He said: "You look awful! You look like someone who's coming down from a cocaine binge!" I thought this was a wacky thing to say, and I did some reading about cocaine and amphetamine withdrawal syndromes. The descriptions I read sounded very familiar. Not only did they resemble my Parnate "discontinuation syndrome," they also resembled the severe and refractory depression I developed after Nardil pooped out (except that I didn't have REM rebound as long as I stayed on Nardil, obviously - though that would have been the least of my troubles).
>
> There are a couple of reports in the literature of people abusing large doses of MAOIs with no apparent cardiovascular problems, BTW. One assumes they had even nastier withdrawal symptoms, comparable to - well, perhaps to the sort of thing one experiences when coming down from a cocaine binge. I also imagine that for people who take moderate doses of Dexedrine, missing a day might be similar to what happens when I skip a day of Parnate (not horrible, but not pleasant either).
>
> And as for treating the "symptom" versus the "disorder:" I disagree. I don't believe you can make this generalization. I think Ativan or Xanax is a fine treatment for panic disorder since they treat both the core symptom of panic attacks and the peripheral symptoms of anticipatory anxiety, phobic avoidance, etc. Similarly, it seems to me that Dexedrine a reasonable treatment for attention deficit hyperactivity disorder, in that it helps people with attention problems, hyperactivity, and impulsivity. (It's also a good treatment for narcolepsy.) I also found buprenorphine (which I'm guessing you would probably class as an "addictive" drug even though it has only a mild and delayed withdrawal syndrome - and of course opiate withdrawal is a classic example of "unpleasant but not life threatening") to be a very good treatment for major depressive disorder (except for the side effects, which were nasty). Am I misunderstanding what you mean when you say that antidepressants treat "the disorder?"
>
> Well anyway, I don't think the difference between "addictive" and "nonaddictive" substances is as clear-cut as one might like.

 

Just started effexor,and i am wondering..

Posted by witchy on June 17, 1999, at 13:52:43

In reply to Re: Effexor Tolerance, posted by stjames on May 4, 1999, at 19:43:05

I just started effexor about 2 weeks ago. After trying almost every drug there is for depression and having real bad side effects from all of them. My doctor has given me this to try.So far the only side effect i am getting is, that it is making me very very tierd i can barley get out of bed.I started taking it a hour befor i go to bed,but it seems that i am still really groggy through the day.Does anybody know how long this will last for??

 

Re: Effexor+Wellbutrin

Posted by Mary Beth on June 18, 1999, at 9:58:26

In reply to Re: Effexor Tolerance, posted by PattyGates on June 6, 1999, at 19:44:52

> My son started out taking Effexor 100 mg. twice daily. When that began to wane, they tried 300, but that was too much. He then tried 150 SR and added Wellbutrin. This combination has been rather successful.

Patty, thanks for this info. I am on the same combination of meds...just added the Wellbutrin this week so haven't seen any change yet. How long did it take your son?

 

Re: Effexor+Wellbutrin

Posted by Patty Gates on June 19, 1999, at 18:39:40

In reply to Re: Effexor+Wellbutrin, posted by Mary Beth on June 18, 1999, at 9:58:26

Hm-m-m-m.....well, the Effexor was extremely quick acting, but the Wellbutrin was along the line of 2 weeks as I recall. He had hoped for it to lift his lethargy (as it does for some) but all he said was that it simply helped him to not care so much *about* the lethargy! Seems more even-keeled and less intense with the added Wellbutrin. Hope the combo works for you!

 

Re: Effexor Tolerance ---> Women and sex

Posted by Sally on June 25, 1999, at 0:39:11

In reply to Effexor Tolerance, posted by Tillman on March 14, 1999, at 21:56:27

I have been taking Efexor for about six months and Depakote for about a year now, and I have been noticing some pretty strange sexual side effects. Every time I orgasm, I lose control of my bladder and urinate. This is not female ejaculation, since it is clearly urine that is coming out. It is very embarrassing not to mention gross. I was wondering if anyone else has been having the same problems. If you do, please email me at medzgirl@yahoo.com.


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