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Re: Selegiline with Bupropion ( Wellbutrin ) ?? Lunette

Posted by DyseaseModel on April 8, 2012, at 23:02:13

In reply to Selegiline with Bupropion ( Wellbutrin ) ??, posted by Lunette on March 2, 2012, at 17:33:21

Welbutrin was way too activating, and I ended up with symptoms of an 80-year-old prostate, and aggression. Selegiline was much better, but you have to dial the dose down after the ramp up to mao-b inhibition.

As an alternative to gabapentin, which I felt was like meditation in a pill (had space to respond rather than react to my most stress-inducing triggers), I moved to tianeptine because of the other effects of gabapentin-- mainly terrible memory/searching for synonyms for words at the tip of my tongue, and clumsiness/inability to learn martial arts forms.

Both selegiline and tianeptine are neuro-protective, and gotten from offshore pharmacies. After many trials of many drugs, this was the best combo.

Always titrate down slowly from whatever you are taking. I would err on safety's side, and not take the chance mixing bupropion and selegiline. Gabapentin limits the spikes causing seizure and similarly limits the spikes in reactive mood and the body's stress response.

Though considered an SSRE (serotonin re-uptake enhancer) as measured against the SSRI dominated world of AD's, tianeptine modulates some of the same gaba pathways that gabapentin does-- very anxiolytic, without the deadening in mood found with ssri's.

It's also great for asthmatics... Your question resonated so much with me that I signed up here after 9 years of by-standing. Good luck!




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