What about amitriptyline + 5HT2C=)weight gain?

Posted by Brainbeard on May 25, 2010, at 6:57:00

In reply to Nortriptyline a 5-HT2c antagonist/inverse agonist?, posted by SLS on April 19, 2010, at 16:45:20

> How potent is nortriptyline as a 5-HT2c antagonist or inverse agonist?
>
>
> - Scott
Yeah, that's what I wanna know too. And the same for amitriptyline!!
Perhaps nortriptyline and amitriptyline's 5HT2C-antagonism is the main reason why they are likely to cause weight gain. I gain weight like crazy on low dose Prozac, which must also be due to 5HT2C-antagonism..
Current meds: 10mg melitracene + 0.5mg flupentixol; sertraline 100mg; amitriptyline 25mg; gabapentin (Neurontin) 300mg; melatonin 0.3mg. PRN: diazepam (Valium) 2.5-5mg.

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Nortriptyline a 5-HT2c antagonist/inverse agonist? SLS 4/19/10
What about amitriptyline + 5HT2C=)weight gain? Brainbeard 5/25/10

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