Posted by Brainbeard on May 23, 2010, at 6:33:27
In reply to differing cannbanoid effects TCA/SSRI, posted by linkadge on March 23, 2010, at 0:34:55
These are just subjective experiences, but on TCA's, I often experience a kind of joyous glow that somehow feels similar to a marihuana high. It's not as strong, of course, but it feels like a mildly euphoric, creative mood. I play guitar and am a singer-songwriter; depression usually robs me of all fun I could have while engaging in playing the guitar and song-writing. Even low doses of a TCA, most notably imipramine and clomipramine, can give me back the glad feeling that there is something enchanting about the tones I hear and produce.
This MAY have something to do with cannabinoid receptors.
Experience often precedes scientific knowledge. I always felt that a marihuana high resembled a state of fever to some extent. Later I learnt that fever can be accompanied by a rush of endocannabinoids.
Current meds: 10mg melitracene + 0.5mg flupentixol; sertraline 100mg; amitriptyline 25mg; gabapentin (Neurontin) 300mg; melatonin 0.3mg. PRN: diazepam (Valium) 2.5-5mg.
poster:Brainbeard
thread:940505
URL: http://www.dr-bob.org/babble/neuro/20100223/msgs/948400.html