Posted by mtdewcmu on December 15, 2009, at 21:52:35
In reply to Re: What about Serzone? » mtdewcmu, posted by conundrum on December 12, 2009, at 16:57:37
> Well i saw that image on the site you linked to. It would seem to put things into perspective except most train accidents are well documented. The FDA believes the reports from nefazodone are only 10% of the actual number of incidents.
>
> So would that make the risk 1 per 30,000 or 25,000 patient years? And what exactly is a patient year? If you're safe on it for 2 years does that mean your liver could still fall out on year 3?
I got that figure from the black box warning, which you can read at http://www.rxlist.com/serzone-drug.htmI believe the FDA had to have approved that warning.
A patient-year is equal to one patient taking the drug for one year. So, your risk of getting liver failure in any given year is 1 in 250,000 to 300,000.
If your liver has made it through two years, it may still fail on the third year, based on that statistic. If you want a better answer, you may want to ask a pharmacist or hepatologist.
poster:mtdewcmu
thread:904542
URL: http://www.dr-bob.org/babble/neuro/20091104/msgs/929482.html