Posted by Meltingpot on May 17, 2009, at 11:25:34
Hello,
I've now been taking clomipramine for about 12 weeks. Have been taking 150mg of clomipramine for the past 5 weeks.
Although my anxiety has decreased, I just feel so tired all of the time. I can hardly get up a flight of stairs without having to stop.
My experience with antidepressants is that if they are working properly, you get an increase in motivation and energy and less anxiety. I therefore don't think this clomipramine is working that well for me.
Last time I went to see my psychiatrist she was discussusing amitryptaline as a possible future option but I was just wondering if anyone on this board has any experience with both these drugs?
I also read the below on this board. Now as clomipramine is supposed to be more hard hitting on 5HT receptors than amitryptaline then does this mean that I've got even less chance of amitriptyline working for me.
> Also, amitriptyline hits most of the antidepressant mechanisms:
>
> * norepinephrine reuptake inhibition
> * serotonin reuptake inhibition
> * alpha-2 receptor antagonism
> * 5ht2a recepton antagonism
> * cholinergic receptor antagonism
Thanks for any advice or experiences in advance.
Denise
poster:Meltingpot
thread:896239
URL: http://www.dr-bob.org/babble/neuro/20090129/msgs/896239.html