Posted by Jamal Spelling on January 29, 2008, at 12:26:35
In reply to Sam-e as an adjunct to an AD, posted by bulldog2 on January 28, 2008, at 14:38:33
SAMe may trigger mania, so that would be a risk to consider when combining it with other ADs.
Some studies suggest SAMe has an efficacy comparable to tricyclic ADs, so it need not be used as an adjunct to prescription ADs. In Italy, SAMe is in fact a prescription AD.
I find SAMe to be highly stimulating. I never use it for more than a month at a time, because (a) it is very expensive, (b) anything that potent almost seems unhealthy, and (c) I do not want to risk permanently altering my neurochemistry from long-term use.
poster:Jamal Spelling
thread:809368
URL: http://www.dr-bob.org/babble/neuro/20080114/msgs/809554.html