Posted by bulldog2 on January 26, 2008, at 17:44:51
In reply to Re: Trivastal and Ixel - End of Day 2, So far So G » bulldog2, posted by atmlady on January 26, 2008, at 17:09:19
> Hi, Bulldog - I'm taking the LA from India, but will probably try the retard version now that I know it's working - it's a pain to have to take 3 times a day. Yes, 50 mg each dose so a total of 150 per day.
>
> Ixel is an SNRI - it's sort of like effexor and cymbalta in that it inhibits the re-uptake of both serotonin and norepinephrine. But unlike those others, Ixel works more on NE than on SE. What I read was that where effexor works on serotonin and NE in a ratio of 30:1 and cymbalta works on them in a ratio of 9:1, Ixel works them on a ratio of 1:3. Not sure if this is why there are less sexual side effects or if that is due to something else.
>
> Ixel has been used as an antidepressant in europe, Japan and south america for several years, and is currently in stage III clinical trils in the US as a treatment for fibromyalgia. If you google fibromyalgia and the brand name ixel (or the drug name milnacipran) you will come across several boards where patients have left glowing reports of the drug's effect on their mood and pain. Many who came off the trials loved the drug so much they continue to buy it on their own.
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> The folks who discontinued the drug did it due to high blood pressure problems or difficulty urinating, and many of those were unhappy that they couldn't stay on it.
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> End of day three and feeling fab!That is quite significant! Cymbalta and effexor are serotonin dominant and the reverse is true for ixel.I personally believe in chemical imbalance but I believe that varies from person to person..So that Ixel might be the right ad for someone where others have failed..Also have tried trivastal ad at 50 mg with limited sucess so I might try 100 mg and see if that improves the combo with luvox. Thank you for your input!
poster:bulldog2
thread:808996
URL: http://www.dr-bob.org/babble/neuro/20080114/msgs/809070.html