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Exercise for severe depression

Posted by linkadge on June 12, 2005, at 15:35:34 [reposted on June 14, 2005, at 22:17:34 | original URL]

In reply to Re: tramadol, posted by Jakeman on June 12, 2005, at 14:12:09

There are quite a number of studies that show that exercise is very effective even in severe depression.

I have been on almost everything. I agree that exercise is extremely hard to do when severely depressed, but I don't doubt its effacacy even in severe depression.

All drugs have pooped out on me, but exercise has never pooped out.

I suppose some say it doesn't work for them. I say throw away the rubber bands, and bump up the intensity.


If the end target of AD treatment is enhanced neurotrophin expression, then exercise has pharmacudicals beat hands down.

Shock - 200% increase BDNF in hippocampus

Exercise - 90-120% increase in BDNF (at 1.5 hours)

Parnate - 40% increase in BDNF in hippocampus


Another intresting thing is that the more exercise, the more BDNF, up to about 8 hours of exercise (at least in rats). I agree 8 hours is not tangable though.


Linkadge


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