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Re: Looking for a good book on statistics Racer

Posted by Quintal on August 5, 2007, at 5:45:20

In reply to Re: Looking for a good book on statistics Quintal, posted by Racer on August 5, 2007, at 1:06:37

Thank you Racer for the excellent suggestions. I settled on "How to Lie With Statistics" and another called "Statistics Without Tears" in the Penguin Science series, which is more on my ability level. The "Statistics for Dummies" got some shocking reviews so I stayed clear of that. I will look into Ian Stewart's work when I've learned to add up and do my times tables and square roots etc off by heart. Someone recommended a basic grasp of calculus as a starting point for one book. I'm sure I've covered it and probably even used it in physics before but I have no idea of what it might be or what it does. Something to do with Issac Newton I believe? He invented calculus did he not?

Well while I await delivery could be so kind as to you enlighten me on the meaning of the term 'P' in this study:

Hum Psychopharmacol. 2007 Jul 24; [Epub ahead of print]Click here to read Links
Effectiveness and acceptability of sertraline and citalopram in major depressive disorder: pragmatic randomized open-label comparison.
Matreja PS, Badyal DK, Khosla P, Deswal RS.

Department of Pharmacology, Christian Medical College and Hospital, Ludhiana, India.

OBJECTIVE: Citalopram and sertraline are widely prescribed selective serotonin reuptake inhibitors (SSRIs). There is no conclusive evidence to show superiority of citalopram or sertraline in terms of efficacy or tolerability. Hence this study was designed to compare short term efficacy and safety of citalopram and sertraline in major depressive disorder (MDD) in Indian patients. METHODS: In an open, randomized study, 100 patients were divided into two groups. In Group A (n = 50) patients received citalopram (20-60 mg/day) for 6 weeks. In Group B (n = 50) patients received sertraline (50-150 mg/day) for 6 weeks. Patients were evaluated at baseline and then at 1, 2, 3, 4, 5, and 6 weeks. RESULTS: There was significant improvement in Hamilton depression rating scale (HDRS), Montgomery and Asberg depression rating scale (MADRS) and Amritsar depressive inventory (ADI) scores (p < 0.05) with both the drugs. However, the decrease in score was more with citalopram (p < 0.05). Onset of action of citalopram was earlier as compared to sertraline (p < 0.05). The number of responders and remitters was also more with citalopram (p < 0.05). No serious adverse event was reported in either of the groups. CONCLUSION: Citalopram had shown better efficacy, earlier onset of action and more number of responders and remitters as compared to sertraline in MDD in Indian patients. Copyright (c) 2007 John Wiley & Sons, Ltd.

PMID: 17647298 [PubMed - as supplied by publisher]





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