Posted by Tomatheus on July 28, 2014, at 10:59:58
In reply to Is high dose Glycine safe?, posted by Lamdage22 on July 27, 2014, at 7:38:10
Lamdage22,
I found a few studies that looked at glycine as an add-on treatment for schizophrenia in patients taking antipsychotics.
Regarding this one:
http://www.ncbi.nlm.nih.gov/pubmed/2611765
-- Participants (six of them) received 10.8 g of glycine a day in three divided doses for anywhere from four days to eight weeks as part of an open-label trial. The participants tolerated the glycine.
Regarding this one:
http://www.ncbi.nlm.nih.gov/pubmed/8037263
-- Fourteen participants received glycine as part of a double-blind, placebo-controlled study. I wasn't able to access the full article, and the abstract didn't state what doses were used, how long the study went on for, or how well tolerated the glycine was.
Regarding this one:
http://www.ncbi.nlm.nih.gov/pubmed/8932891
-- Eleven participants received 0.8 g/kg of glycine a day for six weeks as part of a double-blind, placebo-controlled study. The glycine was well tolerated.
And finally, regarding this one:
http://www.ncbi.nlm.nih.gov/pubmed/9892253
-- Twenty-two participants received 0.8 g/kg of glycine a day for six weeks as part of a double-blind, placebo-controlled crossover study. The glycine was well tolerated.
So, basically taking 0.8 g/kg of glycine for six weeks seems to be well tolerated among patients with schizophrenia. It would be hard to know for sure, though, how safe glycine therapy would be for beyond six weeks.
That sums up what I was able to find. I hope that you're doing well.
Tomatheus
Has a psychotic disorder with strong chronic fatigue symptoms
Taking Abilify, reishi, & vitamins B3 & D3
poster:Tomatheus
thread:1068835
URL: http://www.dr-bob.org/babble/alter/20140619/msgs/1068894.html