Posted by bleauberry on January 15, 2014, at 9:19:23
In reply to Sam-E serotonergic but not dopaminergic?, posted by Lamdage22 on January 5, 2014, at 4:52:54
Short answer to your question:
I've been on SAMe several times over the years, doses from 50mg up to 400mg. I cannot comment on higher doses because I never tried them.
What I felt:
Serotonin...fairly strong, emotional numbing capability.
Dopamine...noticeable but faded.
NE...very little if any felt.But that is only one person's personal report.
Antidepressant effect overall....fairly good. Ask someone else who had a good response and they might say amazing instead.
poster:bleauberry
thread:1057839
URL: http://www.dr-bob.org/babble/alter/20131226/msgs/1058594.html