Posted by Hugh on January 31, 2012, at 13:44:14
In reply to Re: Gotu Kola success stories, dosage info?, posted by bleauberry on January 28, 2012, at 9:11:56
I found the following at http://intelegen.com/nutrients/brain_regeneration_key_nutrients.htm
A breakthrough year occurred in 2005 regarding the number of studies published using Gotu kola extracts on brain function and structural changes. In one study, where Gotu kola was given to mice during postnatal development stage (the) extract caused brain cell dendrite outgrowth and branching of dendrites in the hippocampal area of the brain. This showed the extract can influence the neuronal morphology and promote the higher brain function of juvenile and young adult mice. In other words, permanent structural out branching of the neural network of the brain was observed and this resulted in higher brain functioning.31-32
In the same year, Gotu kola alcohol extract stimulated a marked increase in neurite outgrowth in human brain cells. It was shown than many different fractions of Gotu kola extracts produced neurite branching and outgrowth from the human cells, proving that there are several active principles in Gotu kola causing this growth. These active principals were identified as asiaticosides and asiatic acid. When the alcohol extract was added to the drinking water of old rats (they) demonstrated more functional recovery and increased axonal regeneration (of neurites and dendrites), larger calibers of axons and greater numbers of myelinated (sheath-covered) axons. The authors concluded taken together, our findings indicate that components in Centella ethanolic [Gotu kola] extract may be useful for accelerating repair of damaged neurons.33
The most desirable Gotu kola extract to use is a hydro-alcoholic extract standardized to a much higher percentage of active asiaticoside principles than the vast majority of Gotu kola extracts.
poster:Hugh
thread:1008039
URL: http://www.dr-bob.org/babble/alter/20111229/msgs/1008903.html