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Re: Difference btwn phenylalanine and phenethylamine?

Posted by nolvas on March 21, 2010, at 6:40:50

In reply to Difference btwn phenylalanine and phenethylamine?, posted by Economist on March 20, 2010, at 23:36:26

It's a bit like asking what is the difference between chocolate and cheese. You need a chemist to explain the intricacies. Both compounds contain a phenyl group, however phenylalanine is an amino acid and phenylethyamine is a monoamine alkaloid it is however derived from phenylalanine. So phenylethylamine can be derived from phenylalanine.

Uses for phenylalanine :

L-phenylalanine: Appetite suppression, depression, vitiligo.
D-phenylalanine: Osteoarthritis, Parkinsons disease, rheumatoid arthritis, and pain from a variety of causes, such as chronic back pain, dental pain, menstrual cramps and migraines.
DLPA: Alcohol withdrawal, depression, rheumatoid arthritis, and pain from a variety of causes (due to the action of D-phenylalanine).

Source :

Uses for phenylethyamine:

Some are described in the following links:

Both phenylalanine and phenylethylamine can be used to treat depression. They can also aggravate anxiety or treat anxiety depending on the individual's biochemistry.

Hope this information helps a little, please remember that whilst these compounds can be used for the conditions etc mentioned above they could well have adverse side effects depending on the individual, use only recommended dosages and start at the lowest dose. If you have a condition called phenylketonuria you MUST avoid phenylethylamine and phenylalanine. You will notice that any soft drinks containing the sweetener Aspartame also give a warning to avoid if you have Phenylketonuria.

"Aspartame was first synthesized in 1965. Its use in food products was approved by the United States Food and Drug Administration in 1980. Because its breakdown products include phenylalanine, aspartame is among the many substances that must be avoided by people with phenylketonuria (PKU), a rare genetic condition."




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