Posted by nolvas on April 20, 2007, at 19:56:49
In reply to Any NRI herbs ?, posted by linkadge on April 20, 2007, at 17:51:18
Green Tea may prolong the actions of Norepinephrine (due to the Tea Polyphenols in Green Tea inhibiting the activity of Catechol-O-Methyltransferase (COMT), the enzyme that degrades Norepinephrine).
Green tea and thermogenesis: interactions between catechin-polyphenols, caffeine and sympathetic activity. Int J Obes Relat Metab Disord. 24:252-258, 2000.
The thermogenic effect of tea is generally attributed to its caffeine content. The authors report that a green tea extract stimulates brown adipose tissue thermogenesis to an extent which is much greater than can be attributed to its caffeine content per se, and that its thermogenic properties could reside primarily in an interaction between its high content in green tea polyphenols and caffeine with sympathetically released noradrenaline (NA). Since green tea polyphenols are known to be capable of inhibiting catechol-O-methyl-transferase (the enzyme that degrades norepinephrine), and caffeine to inhibit trancellular phosphodiesterases (enzymes that break down norepinephrine-induced cAMP), it is proposed that the green tea extract, via its catechin-
polyphenols and caffeine, is effective in stimulating thermogenesis by relieving inhibition at different control points along the NA-cAMP axis. Such a synergistic interaction between catechin-
polyphenols and caffeine to augment and prolong sympathetic stimulation of thermogenesis could be of value in assisting the management of obesity.
poster:nolvas
thread:751713
URL: http://www.dr-bob.org/babble/alter/20070410/msgs/751765.html