Psycho-Babble Alternative | about alternative treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Do you have references? » dessbee

Posted by linkadge on January 8, 2007, at 14:00:53

In reply to Re: Why would folic acid help depression? » linkadge, posted by dessbee on January 8, 2007, at 5:44:20

Do you have any references that suggest that SAMe is *only* involved in the synthesis of epiniephrine?


------
http://www.cmaj.ca/cgi/reprint/166/2/205.pdf

"There is a connection between SAMe and serotonin because folate deficiancy can decrease serotonin synthesis in rats and humans, wherase SAMe can increase serotonin synthesis in rats and humans"

"The mechanism of the link between SAMe and serotonin is unknown. SAMe is involved
in over 35 methylation reactions,16 so the possibilities are many."

- Young SN, Ghadirian AM. Folic acid and psychopathology. Prog Neuropsychopharmacol
Biol Psychiatry 1989;13:841-63.

-------
PubMed

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=543840

Administration of SAMe increases cerebrospinal fluid (CSF) 5-hydroxyindoleacetic acid (5-HIAA) in humans4 and brain serotonin in rats,5,6 although the mechanism of this connection between SAMe and serotonin is unknown.

-------

SAMe augmentation of clomipramine causing serotonin syndrome.

: Iruela LM, Minguex L, Merino J, et al. Toxic interaction of S-adenosylmethionine and clomipramine [letter]. Am J Psychiatry. 1993;150:522.

------

http://www.psycom.net/depression.central.same.html

Folic acid deficiency causes a lowering of brain serotonin in rats,
and of cerebrospinal fluid 5-hydroxyindoleacetic acid in humans.

-------

Department of Psychiatry, McGill University, Montreal, Quebec, Canada.

http://www.psycom.net/depression.central.same.html

"and S-adenosylmethionine is an antidepressant that raises brain serotonin levels"...

-------

Affective illness and S-adenosyl methionine: a preliminary report

The indications are that SAM specifically affects folate, dopamine, and serotonin metabolism as well as activating and switching brain
mechanisms

--------

U of Maryland Medical Centre:

http://www.umm.edu/altmed/ConsSupplements/SAdenosylmethionineSAMecs.html

http://biopsychiatry.com/samerev.htm

" SAMe is a methyl donor and is involved in the synthesis of various neurotransmitters in the brain."

-------

http://biopsychiatry.com/sameart.html

"SAMe may enhance the impact of mood-boosting messengers such as serotonin and dopamine—either by regulating their breakdown or by speeding production of the receptor molecules they latch on to. SAMe may also make existing receptors more responsive."

------

"Methylation occurs a billion times a second throughout the body, affecting everything from fetal development to brain function. It regulates the expression of genes. It preserves the fatty membranes that insulate our cells. And it helps regulate the action of various hormones and neurotransmitters, including serotonin, melatonin, dopamine and adrenaline. As biochemist Craig Cooney observes in his new book, "Methyl Magic," "Without methylation there could be no life as we know it."

------

http://www.wandb.com/cgi-bin/shop.pl/page=SAMe.htm

SAMe is necessary in the manufacture of neurotransmitter phospholipids, such as phosphatidylcholine and phosphatidylserine. Additionally, studies show that SAMe can increase levels of the important neurotransmitters serotonin, norepinephrine, dopamine and phosphatidylserine. It has been shown to improve the binding of neurotransmitters to receptor sites, thus increasing brain neurotransmitters, such as serotonin.

------


Linkadge


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Alternative | Framed

poster:linkadge thread:717599
URL: http://www.dr-bob.org/babble/alter/20061218/msgs/720477.html