Posted by qqqsimmons on November 4, 2006, at 9:55:34
In reply to Re: resveratrol improves lifespan, makes you manic, posted by nolvas on November 2, 2006, at 16:39:08
thanks for the info on SAMe and Mg.
i had to find the details:
COMT
FUNCTION: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
CATALYTIC ACTIVITY: S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol.
COFACTOR: Magnesium.
> These Substances may Enhance the Function of COMT >
>
> Amino Acids
>
> S-Adenosylmethionine (SAMe) is a cofactor for COMT.
>
> Minerals
>
> Magnesium is a cofactor for COMT. < hmm that's interesting
>
> These Substances may Inhibit the Excessive Activity of COMT >
>
> Polyphenols
>
> Quercetin may inhibit COMT.
>
> These Herbs may Inhibit the Excessive Activity COMT >
>
> Green Tea may inhibit COMT (due to the Tea Polyphenols content of Green Tea).
> Saint John’s Wort may inhibit the excessive destruction of Catecholamines by COMT.
> Siberian Ginseng may inhibit COMT.
>
>
poster:qqqsimmons
thread:699746
URL: http://www.dr-bob.org/babble/alter/20061013/msgs/700259.html