Posted by sregan on October 2, 2006, at 10:20:23
In reply to Re: 24 hour cortisol salivary results (need help i » sregan, posted by tealady on October 2, 2006, at 0:55:03
> I do think your curve needs restting though, not necessarily "lowering" of cortisol, as it isn't up high all thru the day, and I agree if you do get it "reset" then the highs will probably not be as high.
I read one article that particularly mentioned the CRH overshoot. There are a lot of articles regarding glucocorticoids (and CRH) and depression. In my experience I would go as far to say that my form of depression (which is mostly experienced as sustained anxiety) could be caused completely by the sleep disturbance. The better I sleep the better I feel (less symptomatic) period.
> Do you have difficulty going to sleep at night with that high a cortisol level?
My cortisol is LOW in the evening. Bottom of the scale. I have no trouble falling asleep. It's staying asleep. My awakenings seem to match the CRH/cortisol peaks that start around 3am.
> I tried Tri-cyclic antiD's about 15 yrs ago.. they didnt help me, but we are all individual.
It would be great if one size fit all in this case. Imipramine and mirtazapine are both supposed to be successful at resetting the HPA.
> Also there's a thyroid-pituitary-hypothalamus axis.. and cortisol affects this too, and it affects cortisol..so I think the HPA axis is a bit simplistic (but easier to teach).
Good point, I may need to look into that a little. My problem started with about 6 months of extreme stress and three years later I'm about to bottom out. This is why I've spent so much time looking to the HPA as it is indicated by chronic stress.
> Sorry I can't help, as I feel you know more than me here:)I really do appreciate your time, thank you.
Shawn
poster:sregan
thread:687103
URL: http://www.dr-bob.org/babble/alter/20060817/msgs/691147.html