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Re: Vitamin B1 » Jlx

Posted by tealady on October 1, 2006, at 3:12:39

In reply to Vitamin B1 » tealady, posted by Jlx on September 29, 2006, at 16:47:14

> Hi, Jan,
>
> How much thiamine are you taking? And how much is safe? I was just skimming some of your blog and thought you'd know. :)
>
> JL
>

About 15-20mg every day or second day , if I can get away with it at present (injections of thiamine hydrochloride from canada)
I started in June .. about 60mg to 100mg every second day or so.

But its very variable. Bronwyn (mentioned link under CFS on blog)
http://tealady-health.blog.co.uk/?tag=b1%20headings
took 100mg injections daily for 3 years..and was then in remission and has stayed that wau so far.. couple of years I think. She managed to return finish study full time and get a full time job and feel completely normal now..,.
IN the US they add thiamin to rice and flour so you mightn't be low.
But Bronwyn was taking B1 in a multiB and thought she was covered.. and if I am low, I was also taking at least 20mg in a multi B daily as well...and thought I was covered.
One study.. somewhere on blog
http://tealady-health.blog.co.uk/?tag=pentose

maybe ( I just made these public..werent' b4.. probably not "ready" , but oh well)

I hadn't put this up b4, as I started to look at the pathways.. but decided to work in the garden instead last couple odays and do some painting.. some outdoor funiture I bought 10 or more years ago , finally getting oiled!!
I did sit in on a biochem lecture on this last year but havent looked at or listened to it properly..so I need time to study it!

I was wondering myself, with normal levels being
138 or so for pentose and thiamine reucing this to about 112mg or so in people taking B1(see pdf linked to on pentose tag).. I guess this means it activates this pentose pathway more than usual.. SO
what other pathway should we be using to not need to do this and still feel normal?
Also I found I needed massive doses of B2 and biotin and an incr in Magnesium as well..and suprise.. they are needed in this pathway..as is magnesium. I worked out what I needed from symptoms.. like cracks in corners of mouth appearing ..etc,m then found it matched those utilised in this pathway!
I could take 100mg of B2 in a tablet and urine not be very yellow!.. or still clear for first few days!
so I was using it up.. afte a while I had to reuce to just 25 mg though.
I used to get bright yellow urine just from 5mg of B2!!..so obvioulsy I wasnt using this .. and probably not this pathway much??
anyway, it sometimes is good when what happens matches the theory.

I admit, I need to sit down and study this, but I just don't feel much like study at present..plus I'm overwhelmed with "chores" etc that appear to have buildt up.. sigh

I read somewhere the 'normal" injection amount for people varies from 5mg to 100mg per day. I've seen studies where they used more.. but I definitely wouldn't. There's also been deaths from injections.. they suspect anaphylaxic? so supps may be the thing to try first.
The injections appear to all have been IV's though admiNistered by docs(but its difficult to get deatils on this.. surprised??)..some suspect too fast but noone seems certain of this.. and its probably why they dropped the injections being made in OZ!
I did find 30mg daily too high for me in one dose though.. my legs felt really heavy(bottom half especially the front parts) and I'd get more wiped.
Jan


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