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Re: What exactly is acetylcholine (ACh) ??

Posted by SLS on February 25, 2006, at 13:53:57 [reposted on February 27, 2006, at 19:44:58 | original URL]

In reply to What exactly is acetylcholine (ACh) ??, posted by Meri-Tuuli on February 25, 2006, at 12:56:16

> We're having a 'discussion' on acetylcholine over on the alternative board, and I was hoping some more people might like to contribute?
>
> Here's a link to the start of the tread....
>
> http://www.dr-bob.org/babble/alter/20060130/msgs/612749.html
>
> Thanks!!
>
> Meri


Acetylcholine (ACh) is a substance used as a neurotransmitter, and appears throughout the body. It was the first to be discovered. There are several receptors associated with the function of ACh neurons: those that act like nicotine and those that act like muscarine. The nicotine receptor is a subtype of ACh receptor. However, it is the muscarinic ACh receptor that is most responsible for many of the side effects seen with the tricyclic antidepressants.

Early in the study of the neurobiology of depression, it was speculated that an imbalance existed between ACh pathways and dopamine pathways. Indeed, they do antagonize one another during sleep. At the moment, I am not convinced that ACh neurotransmission is involved in affective disorders.


- Scott

 

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poster:SLS thread:612749
URL: http://www.dr-bob.org/babble/alter/20060130/msgs/613968.html