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Panic disorder - Tryptophan depletion confusion

Posted by nolvas on November 7, 2005, at 18:20:58

Whilst doing my usual browsing on the net I came across this document

http://home.epix.net/~tcannon1/Physioweek14.htm

It clearly states that panic disorder seems to be genetic and obviously the cause appears biological.
It also states that Tryptophan depletion has no effect. However I've found a study that indicates Tryptophan depletion does have an effect.

http://jop.sagepub.com/cgi/content/abstract/16/1/5

So hence I'm a little confused.

CCK4 is also indicated as a trigger for panic and yet CCK antagonist is not effective yeat I believe drug companies are looking in to CCK4 antagonists for anxiety and panic disorder.

If anyone has any thoughts on what I've presented they will be gratefully recieved.


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