Posted by Chairman_MAO on June 20, 2005, at 15:44:44
In reply to Re: Anything to take edge off Wellbutrin? » Phillipa, posted by Maxime on June 10, 2005, at 11:21:25
Wellbutrin is really just a dysphoric stimulant with an antidepressant metabolite (hydroxybupropion, an NE reuptake inhibitor). Thus, since the nature of the drug is such that it produces and unpleasant sense of being wired, there's not much you can do to get rid of that feeling besides lowering the dose or stopping the drug.
I once took wellbutrin while on a ton of benzos and they blunted the anxiety it caused, but that crappy feeling was still there. Best try a more pleasant dopaminergic, such as a REAL psychostimulant, Parnate, DA agonist, or DA releaser (amantadine, memantine, amisulpride). You could add reboxetine or strattera on top of it if you need that adrenergic effect.
poster:Chairman_MAO
thread:511586
URL: http://www.dr-bob.org/babble/alter/20050612/msgs/516085.html