Posted by Elroy on February 16, 2005, at 17:33:23
In reply to Re: Selegiline, posted by world citizen on February 16, 2005, at 11:41:29
Well, have been doing some research on the Picamilon(e). Sounds interesting enough to be worth a try. I just ordered some last night, so will see how it works out (and will post with results).
BTW, I have tried a number of online web sites (such as drugdigest.org) and have found NO interactions for the combination of the following drugs and herbs:
* Selegiline and St. John's Wort
* Selegiline and samE (Sammy)
* Selegiline and Tryptophan or 5-HTP
* Selegiline and Xanax XR
* Selegiline and ValerianIt seems that Selegiline (and most therapeutic doses are actually for Parkinson's and in the 30 - 60 mg range) so I think that the very low dose Selegiline being discussed here is actually extremely safe.
Also interesting info on SJW and it's effectiveness and interaction with other drugs found at following web sites:
http://my.webmd.com/content/article/100/105807
New research shows the herbal supplement St. John's Wort to be as effective as one of the most popular prescription antidepressants for treating both moderate and severe depression... researchers treated 251 patients with major depression with either a standard dose of the St. John's Wort extract (900 milligrams a day) or the antidepressant Paxil (20 milligrams a day)... 71% of the patients taking St. John's Wort and 60% of those taking Paxil had responded to treatment. Half of the St. John's Wort-treated patients and 35% of the Paxil-treated patients were free of depression symptoms... concerns have been raised in recent years about interactions with other medications. It has been shown to decrease the effectiveness of some lifesaving drugs, including those that fight cancer and AIDS, and drugs, such as cyclosporine, that prevent organ rejection after a transplant... study published in the fall of 2003 showed that taking the herbal supplement reduces the effectiveness of as many as half of all prescription and over-the-counter drugs...I know that there's an interaction with Xanax so would not even consider taking it until I was weaned off the Xanax (but probably would be okay taking Theanine while on the Xanax until I could wean off???).
Also at:
http://www.npicenter.com/anm/templates/newsATemp.aspx?articleid=11690&zoneid=41
According to a randomized, double-blind, reference-controlled clinical study published today in the prestigious British Medical Journal, the proprietary St. John's Wort extract WS(R) 5570 is at least as effective in treating depression and better tolerated by patients than the widely prescribed anti-depressant paroxetine.(1)... n the U.S., an identical strength version of WS(R) 5570 is sold as a natural dietary supplement for promoting a positive mood, rather than a drug for the treatment of depression. This extract (WS(R) 5572) contains the same patented, standardized and stabilized hyperforin content as WS(R) 5570, and is marketed as Perika(R) St. John's Wort by Nature's Way Products, Inc., Springville, Utah. Perika(R) is available nationwide at health and nutrition retail outlets...
http://store.yahoo.com/iherb/perika.html $8.00 and change for 60 tabs but at 300mg per tab and needing to take 900mgs, would need be like $25 for a 2-month supply... however this one IS cheaper at VitaCost...
http://www.vitacost.com/Store/Products/ProductDescription.cfm?SKUNumber=033674065600&searchby=PN&SearchText=Perika
$6.99 for 60 tabs but at 300mg per tab and needing to take 900mgs, would need be like $21 for a 2-month supply...
Unfortunately all still speculation at this point as still awaiting word from psych doc in getting prescribed the Selegiline... am still hoping though to give the Selegiline and DLPA (and Vit B6, etc.) a chance.I'd sure like to make a posting like the last one from Pseudonym...
http://www.dr-bob.org/babble/20041211/msgs/430276.html
Elroy
P.S. Thanks for the information on THEANINE SERINE from Source Naturals. That sounds very promising. Will definitely look into it. BTWm iHerb has it much cheaper:
http://store.yahoo.com/iherb/theanineserene1.html
Plus a version with Relora (anti-cortisol) added in (that also is still cheaper)
http://store.yahoo.com/iherb/theanineserene.html
Serving size:2 Tablets
Servings Per Container: 30
Amount Per ServingMagnesium (as magnesium chelate) 300 mg
GABA 500 mg
Taurine 450 mg
L-Theanine 200 mg
Relora (a proprietary blend of patent pending plant extracts from Phellodendron amutense and Magnolia officinalis ) 150 mg
Valerian Root Extract 100 mg
>
>
> Hey Elroy,
>
> I'm not at all convinced the GABA taken orally passes the blood-brain barrier-even with niacin. As far as St. JOhns'Wort, I'd HIGHLY advise against taking it along with Selegiline as the researchers believe it has several modes of action in terms of acting as antideprossant. Your might want to consult with several pharmacists and get a consensus on this. I would think it would be easier to take a good valerian root extract as this DOES pass the blood-brain barrier, attends to similar GABA receptors as the benzos., AND is not contraindicated with Selegiline. I'm investigating a suppliment that contains L-theanine, taurine, magnesium, GABA and valerian.
> Here's the rendown: THEANINE SERINE from Source Naturals. composition; 60 tabs
>
> Mag. chelate 300mgs
> GABA 500mgs
> taurine 500mgs
> theanine 200mgs
> valerian 100mgs
>
> This product is being offered at VITACOST.COM for
> about $16.00. Seems like a good investment to me
> World Citizen
>
>
>
> > Thanks for info. Am going to try and convince my psych doc to go with the selegiline option (low dose with DLPA, Vit 6, etc.) and see how that works out. If effective at eliminating depression would then like to gradually wean off the Xanax XR and go with something more antural. You think L-theanine would be a better option than say a SJW... or how about the Nootropic compound picamilone (seeing as how it is a combo of Niacin and GABA)?
> >
> > Elroy
> >
> >
>
>
poster:Elroy
thread:452259
URL: http://www.dr-bob.org/babble/alter/20050131/msgs/458930.html