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Re: Do conversions along pathways go both ways? » tealady

Posted by raybakes on November 1, 2004, at 6:52:57

In reply to Re: Do conversions along pathways go both ways? » raybakes, posted by tealady on October 29, 2004, at 20:50:57

> >I'm a bit confused as to the link between glutamine and glucosamine? I had a quick look and couldn't see it.
>
> OK I found it I think..top line of this
> http://www.genome.jp/kegg/pathway/map/map00251.html
>
> so that kinda has something to do with G6PD(or something close) I think?
>

Hi Jan, not sure if it's directly anything to do with G6PD but i'm more interested in it as part of of the extracellular matrix, to help with my gut wall. Also came across this when looking up something to send you...

Recombinant human TSH is glycosylated with mannose, N-acetylglucosamine, fucose, galactose, and NANA.84 Higher levels of NANA confer longer circulatory life.84 Carbohydrate removal impairs TSH bioactivity.84 Patients with hypothyroidism have TSH with more NANA relative to sulfation.37 Patients with idiopathic central hypothyroidism have glycosylation changes in their serum TSH.85



http://www.glycoscience.com/glycoscience/document_viewer.wm?FILENAME=H286Bve glycosylation changes in their serum TSH.85

It seems that TSH needs four saccharides attached for it to function efficiently - I wonder if TSH can rise to counter a saccharide deficiency?

What did you think about the ideas to do with nitrates, and sulphites and vasodilation? (acetylcholine/vaspressin thread)

Ray


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URL: http://www.dr-bob.org/babble/alter/20041022/msgs/409939.html