Posted by karaS on September 15, 2004, at 21:16:02
In reply to Re: Selegiline Phenylalanine nemesis, posted by nemesis on September 15, 2004, at 8:16:26
Nemesis,
Thanks so much for all of your information.
I'm wondering if the stimulation much later in the day isn't more than just a minor reaction. I tend to react paradoxically to stimulants and I'm wondering if this will be the same way. I know that most stimulants don't work on PEA but I'm wondering if I have hypersensitive dopamine autoreceptors which would still end up giving me a lot of problems with selegiline. I guess I'd have to do the experiment to be certain but it's hard to work at all if you're having such strange reactions. I'll have to look into all of this more once my schedule is a little more stable.
Also, have you tried any other brands of DLPA and P5P? I have NOW brand P5P here but it also adds in a little zinc and something else. I wonder if that's a problem. The DLPA I have at home is Twinlab and Source Naturals. One is a capsule and the other is a tablet. Wonder if any of that matters too. I usually order from iHerb.com because their prices are good - but they don't carry Solgar.In terms of the selegiline, are you using pills or liquid? I've read that the liquid is better but that could just be more of a political issue.
I know that the patch isn't the same as what you're doing with adding in the raw materials from the DLPA - yet some treatment resistant depressives have reported great success when they used the patch in experimental trials. These same people have tried the pill form of selegiline with limited success. (Don't know if they tried adding in any DLPA.)
Anyway, sorry for running on so. I'm just very interested in this and I would love it if I could figure this all out and make it work for me.
Take care,
Kara
> The first couple of days I had a variety of minor odd reactions, including headaches. These all passed within 3 days. The issue with insomnia took longer to pass, but it did. For the first week or two, there were a few nights when I had to take a couple Xanax or a few Neurontin and a half a Xanax in order to sleep. That also has passed, though. No need for the Xanax at all now, and I use the Neurontin only on the occasional odd day if my anxiety is up. Most new meds seems likely to come with some side effects, at least temporarily (Pamelor gave me paradoxical insomnia for months, not to mention other side effects that persisted the entire time I took it . . . constipation, dry mouth, weight gain, etc.). I'd stick it out for a few weeks and see how you feel. As for the patch, it's just going to be an MAOI unless you add in the DLPA for the extra kick.
>
> > I am not taking this now. I tried taking just selegiline 5 mg. for a couple of days. (I was going to add DLPA in the following days and possibly up the dosage of the selegiline to 10 mg. as the experiment progressed.) I had a somewhat paradoxical reaction to it though. I took it at around noon time and felt tired for most of the afternoon (had to drink a full cup of coffee which I don't usually do in the afternoon). Then around 9:00-10:00 that evening I started feeling the stimulation from it and couldn't sleep. So I decided that this might not be the best thing for me to try right now. I haven't given up on it entirely though (I just think that there may be some other health-related reasons that are standing in the way of this working well for me now) and I'm still holding out hope for the patch.
> >
> > Nemesis, if you have any insight into why I might have reacted like I did to the selegiline, I'd love to hear it. It would be easier to understand if I just had the initial paradoxical reaction. I don't suppose you reacted like that to it at first, did you?
> >
> > I would love for this combination to work for me. It sounds so ideal - easy, inexpensive, clean and yet brain healthy (or so they claim).
> >
> > Also, do you take anything for sleep with this regimen? It doesn't sound like it but I just wanted to be sure.
> >
> > sfy,
> > If you do decide to try this, please post your results. I'd be very interested in seeing how your fared on it.
> >
> >
> > Kara
> >
> >
> >
> >
>
>
poster:karaS
thread:377600
URL: http://www.dr-bob.org/babble/alter/20040901/msgs/391288.html