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Re: Serotonin, anxiety and diet » emil

Posted by Kacy on February 17, 2004, at 20:42:29

In reply to Serotonin, anxiety and diet, posted by emil on January 12, 2004, at 15:12:50

Hope you are still checking back. I just saw some information on this. My own experience is consistent with the study. Strattera reduced my anxiety. It is an norepinephrine (ne) reuptake inhibitor. Even without stimulants or supplements added on, Strattera was effective for that. Others have posted the same benefit with Strattera.

I re-write the articles sometimes if I'm interesting in keeping the information. Here's my short version and the link to the other.


http://biopsychiatry.com/noranx.htm

Depletion of brain norepinephrine:
differential influence on anxiolyic treatment effects

Anxiety can be treated by

(1) Temporary treatment with anti-anxiety drugs like benzodiazepines or barbiturates
(2) Long-term treatment with tricyclic (TCA) or monoamine oxidase inhibitor (MAOI) anti-depressants.

Objective: Determine the effects of ne depletion on the two different treatments.

Methods: Rats

Results:
• Reducing ne increased anxiety.
• Despite pre-treatment to reduce ne, alprazolam or phenobarbital still reduced anxiety.
• In contrast, pre-treatment to reduce ne completely abolished the anxiety-reducing effects of desipramine or non-selective MAOI phenelzine treatment.

Conclusions: Noradrenergic neuronal integrity appears necessary for reducing anxiety when using antidepressants, but isn't necessary to get anxiety relief with barbiturates and benzodiazepines.


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poster:Kacy thread:299897
URL: http://www.dr-bob.org/babble/alter/20040110/msgs/314898.html