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Larry need some biochem advise

Posted by Robert Fairburn on November 2, 2003, at 15:24:53

larry I wonder if you could give me some advise on why Im deficient in serotinon.

I know that this is a large question but I'll try and provide you with as much relevant info as possible. I have a high count in Noradrenaline and Dopamine, which would indicate that there is no enzymic problems in the creation of these neurotransmitters. This in effect would wipe out Vitamin B6 as a problem. I am low in Magnesium and Zinc, however, I am not sure that these two metals are rate limiting for the conversion of Trytophan to 5-HTP. I have heard that Vitamin B3 creation absorbs any spare Trytophan and converts this into B3. This occurs at a ratio of 60:1 in comparison to creation of 5-HTP. I know that I have low serotinon through blood tests. However most serotinon resides in the Enteric Nervous System of a ratio of 9:1 compared to the CNS. Do you know of any studies that shows that there is a correlation between low plasma levels in blood and CNS levels.

PS I suffer from anxiety OCD which is also another contributing factor into me believing that I am suffering from low serotinon.

Regards,

Robert


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poster:Robert Fairburn thread:275826
URL: http://www.dr-bob.org/babble/alter/20031023/msgs/275826.html