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Re: Lar, Re: Gaba, Blood brain barrier » Gabbix2

Posted by Larry Hoover on September 21, 2003, at 5:37:33

In reply to Lar, Re: Gaba, Blood brain barrier, posted by Gabbix2 on September 7, 2003, at 20:23:35

> I *thought* GABA worked for me, but now after hearing almost equal arguments about whether or not it even passes the blood brain barrier,
> I'm wondering if it was just what I was told to take with it that actually helped me relax.
> Is there any definitive research on that?
> Thanks

Sorry, Gab, but I missed this post.

Oral GABA will have peripheral effects (i.e. outside the central nervous system), without doubt. There is fairly strong evidence that GABA does not cross the blood-brain barrier (BBB) in substantial amounts, but that doesn't mean that none gets across, or that you aren't getting more than the average uptake across *your* BBB. There's no reason to try and convince yourself that you were having a placebo response. Frankly, I don't think it matters, one way or the other. What works works, non?

Lar

 

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