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Lumateperone (Caplyta) for depression?

Posted by SLS on January 7, 2023, at 7:25:32

Has anyone tried lumateperone (Caplyta) to treat depression? This drug was approved by the FDA in 2019 as an antipsychotic to treat schizophrenia. In 2021, the FDA approved lumateperone for both Bipolar I and Bipolar II depression.

Is lumateperone superior to lurasidone for treating depression?

This article describes a clinical trial using lumateperone for treating:

- Bipolar I Depression
- Bipolar II depression

* Major Depressive Disorder (MDD) - Clinical trials are ongoing.


"Efficacy and Safety of Lumateperone for Major Depressive Episodes Associated With Bipolar I or Bipolar II Disorder: A Phase 3 Randomized Placebo-Controlled Trial"

- Scptt

Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.




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