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Ketamine response inadequate? - Add magnesium

Posted by SLS on January 1, 2023, at 6:31:39

I was thinking about Beckett2's case earlier today, and I played out a hunch. I recall a paper I read long ago that described an interaction between magnesium and glutamate at the NMDA receptor. Somehow, the magnesium facilitated a greater degree of receptor antagonism demonstrated by ketamine.

I like puzzles.


"Combination of ketamine and magnesium in a normal magnesium level presents a superadditive effect in depression treatment."


- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.




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