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Re: SLS, anyone: taking Seroquel and propranolol

Posted by undopaminergic on December 25, 2022, at 11:02:49

In reply to SLS, anyone: taking Seroquel and propranolol, posted by Jay2112 on December 15, 2022, at 20:15:53

>
> But, I am wondering about taking Seroquel XR along with propranolol. I am looking help balance my norepinephrine levels...as Seroquel has a norepinephrine agonist as a metabolite.
>

Quetiapine (active ingredient of Seroquel) or its metabolite norquetiapine is not an adrenergic *agonist*, but an *antagonist*. It has the highest affinity for histamine H1-receptors, and the next highest is for alpha1-adrenoceptors. This would imply that it may cause orthostatic hypotension.

> Oh, and undopaminergic, I am doing well on vortioxetine as well, too. I hope you are still doing well, too.
>

I'm still enjoying occasional mood peaks from it.

-undopaminergic


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URL: http://www.dr-bob.org/babble/20220917/msgs/1121343.html