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Re: Neuroleptics decrease bladder voiding?

Posted by undopaminergic on October 23, 2022, at 9:47:35

In reply to Neuroleptics decrease bladder voiding?, posted by Lamdage22 on October 22, 2022, at 11:37:13

> Now the urologist wants me to take saw palmetto to help. But it does curb DHT, a potent androgen. Are there alternatives? I am worried about my virility.

Dihydrotestosterone (DHT) is considerably more potent than testosterone, so you might think it is better than the latter, but that is not true for muscle tissue; citing from Wikipedia:
<<In addition, unlike testosterone, DHT is inactivated by 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD) into the very weak androgen 3alpha-androstanediol in various tissues such as muscle, adipose, and liver among others, and in relation to this, DHT has been reported to be a very poor anabolic agent when administered exogenously as a medication.>>

I'm not up to date about the pharmacology of saw palmetto, but finasteride and dutasteride, by inhibiting DHT synthesis, increase testosterone (but also estradiol; maybe you could add anastrazole or a similar drug to prevent that).





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