Posted by undopaminergic on September 29, 2022, at 6:13:35
In reply to Clorgyline is a MAOI specific for MAO-A., posted by SLS on September 28, 2022, at 13:52:49
> However, low dosages of selegiline inhibit MAO-B only, which is sufficient for treating Parkinsons Disease. Parkinsons
>In the case of selegiline amphetamine metabolites are also involved to an extent. This does not apply to rasagiline.
> is a movement disorder caused by the deterioration of dopamine neuron terminal buttons.
>I'm pretty sure the whole cells are affected. They go through apoptosis.
> MAO-A - Norepinephrine and Serotonin
> MAO-B - Norepinephrine and Dopamine
>MAO-A metabolises dopamine, and is indeed more involved in that process than MAO-B. I don't think MAO-B breaks down norepinephrine; its preferred substrate seems to be phenylethylamine (PEA).
-undopaminergic
poster:undopaminergic
thread:1120765
URL: http://www.dr-bob.org/babble/20220917/msgs/1120816.html