Posted by rose45 on April 1, 2022, at 12:05:47
In reply to Re: combining nardil and parnate ) SLS, posted by SLS on April 1, 2022, at 10:08:46
> > > True, you can also try Psychotherapy or lifestyle changes. Hope does not have to rely solely on new drugs. I only get excited when really new stuff comes out that does not go into the me-too category. Some meds are less 'me too' than others. Those are the ones that excite me. I would get excited for a Neuroleptic without metabolic side effects for example.
> > >
> >
> > There are already neuroleptics with low risk of weight gain. In a nutshell, they are drugs without antihistamine effects. Examples are haloperidol and amisulpride.
> >
> > What would excite me more is antipsychotics without antidopaminergic effects.
> >
> > -undopaminergic
> >
>
>
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> There certainly are neuroleptics that have a reduced incidence of weight-gain. However, it may be that none of those drugs make effective bridges to be used to reduce the intensity of withdrawal syndromes or preventing a full relapse.
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> A "bridge" is meant to be a temporary treatment to mitigate any suffering that occur during a washout period.
>
> For me, I think there are 2 drugs that make good candidates tor being a bridges.
>
> 1. Zyprexa (olanzapine)
> 2. Saphris (asenapine)
>
> Although Abilify (aripiprazole) might work well to mitigate an antidepressant withdrawal syndrome, discontinuing it is problematic and produces anxiety as its own withdrawal syndrome.
>
>
> - ScottIsn't Olanzapine also very difficult to come off?
rose45
poster:rose45
thread:1119086
URL: http://www.dr-bob.org/babble/20220128/msgs/1119212.html