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Re: Real World data and new drugs

Posted by undopaminergic on October 7, 2021, at 10:31:17

In reply to Re: Real World data and new drugs, posted by SLS on October 6, 2021, at 22:30:22

> I post regularly regarding the higher rate of reported placebo effect and lower rate of efficacy as reported in today's antidepressant clinical trials compared to those conducted in the 1970s and 1980s. To explain this, one must take into consideration the differences in subject selection and inclusion criteria. Today's trials dilute the subject population by including subjects who do not really have Major Depresive Disorder. They are experimenting using people who don't really have the illness that they are supposed to be studying.
> Oh, well.
> Money.
> Investigators are paid by the numbers of participants they recruit.
> - Scott

Money? Isn't there more money to be made from showing efficacy of the drug? So, they would want to choose subjects that will respond better to the drug, wouldn't they?





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