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Re: Introduction to nicotinic receptors and nicotine

Posted by undopaminergic on September 29, 2021, at 8:18:59

In reply to Re: Introduction to nicotinic receptors and nicotine, posted by linkadge on September 28, 2021, at 16:07:23

> Interesting. Apparently cotinine is a serotonin reuptake inhibitor and has antidepressant properties.
> Linkadge

From Wikipedia: "Similarly to nicotine, cotinine binds to, activates, and desensitizes neuronal nicotinic acetylcholine receptors, though at much lower potency in comparison. It has demonstrated nootropic and antipsychotic-like effects in animal models. Cotinine treatment has also been shown to reduce depression, anxiety, and fear-related behavior as well as memory impairment in animal models of depression, PTSD, and Alzheimer's disease."





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