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Re: Damage from one-time meth use

Posted by undopaminergic on November 5, 2020, at 12:27:27

In reply to Damage from one-time meth use, posted by amd on November 5, 2020, at 11:53:19

> I smoke some crystal meth two evenings ago -- probably two or three hits off a pipe. I combined this with cocaine, alcohol, and marijuana. I ended up staying up about 30 to 35 hours before I crashed.

Don't worry about that. I've been up several days, maybe a week.

> What I want to know is, having never done crystal before, what kind of long-term damage might I have done?

Very little damage. Long-term use at high dose does produce significant damage though.

> I feel absolutely toxic today, tired, depressed, and jittery. I feel hopeless, frankly. Did I completely ruin my brain from the few uses that night?

No, you didn't. What you are describing is a typical "come-down" syndrome. It is normal fatigue, from having stayed up long, compounded by the withdrawal effects of the drug. Meth releases dopamine, which produces a high, but this drains the stores of the neurotransmitter, and it will take some time before the levels are back to normal,

If the low persists, it is hardly due to physical damage, but more likely due to a failure of homeostasis, which means there is a chemical imbalance remaining, and this may mimic depression (or burnout). This, however, is too early to tell in your case.

That said, however, there is also a possibility that the drugs you took were contaminated with more toxic substances. Some toxins *can* produce rapid damage.





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