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Re: Effexor vs TCA+SSRI?

Posted by undopaminergic on September 10, 2020, at 11:56:27

In reply to Re: Effexor vs TCA+SSRI?, posted by Christ_empowered on September 10, 2020, at 10:20:18

> I'd avoid tca if possible.

From the point of view of side effects, it is generally a good idea to avoid TCAs. However, the TCAs (not to mention MAOIs) are often more effective than (especially) SSRIs.

Trimipramine (a TCA) by far more effective than the SSRIs I've tried (most of them). It does have disturbing anti-histamine side-effects, but I've not noticed any sexual adverse effects. And the sedative (anti-histamine) effects can be exploited to facilitate sleep.





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