Posted by SLS on July 7, 2020, at 20:58:57
In reply to Re: MAOI frustrations, posted by rjlockhart37 on July 7, 2020, at 13:40:28
Just a quick correction, RJ.
Moclobemide is a reversible inhibitor of MAO-A. It is my impression that MAO-A is more important for depression than MAO-B.
Moblobemide does not often produce a lasting improvement. Most people find themselves escalating the dosage quickly to retain any benefit until they reach the maximum dosage of 1200 mg/day, and then there's nowhere to go. The only theoretical advantage to moclobemide is that its reversibility doesn't require one to follow a low-tyramine diet. But it is its reversibility that probably makes it such a crappy antidepressant.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.The only thing necessary for the triumph of evil is that good men do nothing.
poster:SLS
thread:1111098
URL: http://www.dr-bob.org/babble/20200511/msgs/1111190.html