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Latuda for depression - bad side effects? PeterMartin

Posted by Reggie BoStar on August 26, 2019, at 9:18:57

In reply to Re: Latuda for depression - bad side effects?, posted by PeterMartin on August 26, 2019, at 1:56:30

> Curious though, what generic manufacturer makes the Wellbutrin you're taking? The pills have been consistent (same brand)?
> I've read Wellbutrin is one of those meds that has some bad generic makers. If you recently filled that bland got switched brands that could be causing issues too.

I haven't had any bad experiences with Wellbutrin generics that I can remember. However separating a bad generic batch from all the other variables affecting treatment quality would be tough to do, especially with psych meds. The only consistent thing I've been able to do is watch for any changes in any one med.

In this case it was the change from no Latuda to Latuda, not a change in generic mfgs, so I think it's fair to ID it as the cause of the malaise.

The following is TMI about trying to ID generics. You reminded me of why it's essentially impossible nowadays. If you're interested in that, read on. If not, I'll be sticking to problems with my Latuda Rx in future posts in this thread.

************************************
The TMI:

My Wellbutrin's generic was the same before/after Latuda, so there were no changes there that could have caused the side effects - unless, of course, the generic mfg changed its own source for the drug. But how could you track that? Does the mfg really make it, or repackage ingredients from wholesale sources? No way to know.

The current mfg for my Rx of "Buproprion HCL XL" is SciGen Pharmaceuticals, Hauppauge NY, "manufactured for Dr. Reddy's Lab". That's two places where the generic could be botched. In 2008 SciGen had to recall Irbesartan (hypertension med)
because it contained a carcinogenic contaminant. Does that mean their Wellbutrin generic is necessarily suspect? Again, how would I know? SciGen could have purchased wholesale lots and/or ingredients of both drugs from different sources, anywhere in the world.

Previous to that (most of last year) the mfg for my Wellbutrin generic was Par Pharmaceuticals. They're "headquartered in Chestnut Ridge NY" but are part of the "ENDO International Company". Supposedly it's USA based but registered in Ireland for tax purposes. They buy other pharmaceutical companies from...? Do they also wholesale drugs and ingredients from...? When they buy another pharmaceutical, do they just slap their label on drugs manufactured wherever that company is?

It's a mess. Generic brand names mean nothing. The only thing that matters is performance, because there's just no way to ID where any generic at any time is really coming from.


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poster:Reggie BoStar thread:1105903
URL: http://www.dr-bob.org/babble/20190728/msgs/1105911.html