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Re: Amitriptyline and bipolar... Playing with fire? PeterMartin

Posted by SLS on August 18, 2019, at 11:25:03

In reply to Re: Amitriptyline and bipolar... Playing with fire?, posted by PeterMartin on August 17, 2019, at 15:15:34

Hi, Peter.

My doctor once said that there are no effective antidepressants that are not capable of producing mania in some percentage of people. Traditionally, it has been thought that tricyclics are the worst offenders. Interestingly, there were a few research doctors in the 1980s who thought that Wellbutrin might prevent mania rather than cause it. This turned out to be wrong. Still, some still regard Wellbutrin to be less apt to cause mania than other antidepressants.

Why did you stop taking Marplan? How would you compare it to Nardil with respect to efficacy and side effects? Weight gain?

Thanks.


- Scott


> I'd recommend searching Pub Med for studies on using tricyclics w/ bipolar: https://www.ncbi.nlm.nih.gov/pubmed/
>
> I'm BP1 and I've always been told that of the different classes TCAs are the most likely to cause a manic switch.
>
> I currently take Nardil. Took Marplan before for 7yrs. No probs.



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