Posted by Hordak on July 28, 2019, at 16:06:44
In reply to Re: I need some advice regarding my medication regimen, posted by Christ_empowered on July 28, 2019, at 12:20:29
> hi. the tca drugs are...perhaps not surprisingly...rather toxic. remember; the original tca, imipramine, was supposed to be a rip off of Thorazine. when tested in hospitalized people, the 'schizophrenics' got worse, and the 'severe depressives' got a mood lift...and about 1/4 of them turned manic.
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> there is one...i've never taken it, i don't know if its available where you live....surmontil. it is sedating, a later developed tca that somehow helps get to sleep and then doesn't produce the artificial, not so refreshing sleep of most sedatives...
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> and i think its more closely related to clozapine...i forget the specifics, but its supposed to be helpful for the more agitated depressives among us, less cardio-toxicity, wide dosage range, etc. etc. etc.
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> it also dawned on me...remeron+wellbutrin. the remeron could possibly help improve appetite, the wellbutrin is a relatively mild stimulant, one of the less apathy-inducing drugs out there.
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> is gabapentin an option? even on an as needed basis, i would think it might be helpful, particularly during the antidepressant start up period.
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> just some random thoughts. i hope things get better for you.Thanks man!
surmontil is Trimipramine... we've got it in Germany. It is being used as a sedative, but has most probably no antidepressive effects!? Very strong H1 and strong HT2A & alpha1-adrenergic antagonism. Somewhat related to Mirtazapine when it comes to function.
My biggest fear when it comes to TCAs is constipation and orthostatic hypotension :=D
Wellbutrin is an interesting drug, BUT I have anxiety and weight gain issues, so I am not sure if it's wise to take it :=D
Gabapentin, Pregabalin are definitely an option, but in the end the psychiatrist has to decide... O_o
poster:Hordak
thread:1105412
URL: http://www.dr-bob.org/babble/20190728/msgs/1105477.html