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Ritalin + MAOi - Will benefits appear over time?

Posted by PeterMartin on June 15, 2019, at 22:34:25

I currently take Marplan (MAOi). I've had issues w/ sleepiness and lack of motivation for a few years now (including through a trial on Nardil last year). My doctor suggested/oked adding a 5mg dose of Ritalin to my medicine regime.

I've taken Ritalin before up to 60mg. It was effective but generally short lived (tolerance) and with a peak at ~an hr and then an anxious come down.

It's only been 3days taking the 5mgX2 w/ my current cocktail (Marplan 40, Lamictal 250, Metformin 1000, Seroquel 25 for sleep). The first day I felt pretty good. The 2nd and 3rd kinda blah to be honest. I still get a little peak / burst of feeling good/interest an hour or two after taking it but shortly thereafter I find myself not wanting to do anything at all.

There were a few times where I felt like maybe it was helping but it'll just take some time for me to stop expecting a caffeine type burst (that I definitely used to get on higher dosages of Ritalin).

My question though is since I'm taking Marplan will the effects of Ritalin build up? Like I have higher dopamine levels after a week or two of taking this small dose of Ritalin? Or will it still more or less act in the short term?

I have a blood pressure cuff and surprisingly my blood pressure has been on the low end as it usually is on Marplan. Today at 7pm after an AM/5PM dose of Ritalin it was 97/60 pulse 95. So as far as using them together everything seems ok there.

I guess I'm just hoping using Ritalin consistently will maybe kickstart Marplan a bit. My moods haven't been great the past few weeks. I have good days and days where I just sleep, get up to pee/take my dogs to pee, and then sleep.

If anyone has any words of encouragement I'd appreciate them :)


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poster:PeterMartin thread:1104877
URL: http://www.dr-bob.org/babble/20190513/msgs/1104877.html