Posted by mtom on June 2, 2019, at 19:09:11
In reply to Re: Mirtazapine/Remeron recent experience, SE's, etc?, posted by linkadge on June 1, 2019, at 16:16:07
I can't find a lot of patients reports. Most responses to this post talk about it for insomnia, which is not my biggest challenge right now (has been on and off in past).
Lancet found it #2 for efficacy for depression in a review study:
https://www.thelancet.com/action/showPdf?pii=S0140-6736%2817%2932802-7
It is also widely prescribe off label for anxiety.I've found a few other studies showing it effective for depression as add-on medication. However one large review study found no evidence of a clinically significant benefit as add-on (although they describe lots of possible reasons for this and why more studies might be needed) - and they grouped all SSRI's and SNRI's together - didn't comment on head to head results, just did an average as far as I can tell.
Conversely there was another study, although smaller, published more recently, that specifically found clinical improvement in depression when Mirtazapine was added to escitalopram.
Wish some of the patients from these studies who found it effective were reading this forum and could comment......
I don't like subscribing to other forums because of their privacy policies. Also - as has been noted by posters in past, most people subscribing to AD forums are those "not" happy with their meds, people doing well don't tend to post as much......
poster:mtom
thread:1104640
URL: http://www.dr-bob.org/babble/20190513/msgs/1104725.html