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Re: Do any antidepressants work better in men? » Martinchen978

Posted by linkadge on December 19, 2018, at 16:14:38

In reply to Re: Do any antidepressants work better in men?, posted by Martinchen978 on December 19, 2018, at 13:44:25

>Perhaps they work better in men because men wait longer until diagnosis and are more depressed than women when diagnosed.

Possibly, but usually groups are randomized to control for depression severity (i.e. both groups contain, on average, patients with the same average depression severity.

I agree with SLS though, that there is ample evidence that there are real differences in biology. Both male and female sex hormones are neuroactive and impact brain development in different ways. Taking testosterone vs. estrogen have distinct behavioral effects.

Linkadge


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